N-(1-Benzyl-pyrrolidin-3-yl)-2-chloro-acetamide

Base Information

Chemical Name:N-(1-Benzyl-pyrrolidin-3-yl)-2-chloro-acetamide
CAS No.:939758-04-0
Molecular Formula:C₁₃H₁₇ClN₂O
Molecular Weight:252.744
Hs Code.:
DSSTox Substance ID:DTXSID10585353
Mol file:939758-04-0.mol

Synonyms:N-(1-Benzyl-pyrrolidin-3-yl)-2-chloro-acetamide;939758-04-0;N-(1-benzylpyrrolidin-3-yl)-2-chloroacetamide;DTXSID10585353;AKOS000118211;AKOS017283091;AM101670

Suppliers and Price of N-(1-Benzyl-pyrrolidin-3-yl)-2-chloro-acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
N-(1-Benzyl-pyrrolidin-3-yl)-2-chloro-acetamide 95+%
1g
$ 544.00

American Custom Chemicals Corporation
N-(1-BENZYLPYRROLIDIN-3-YL)-2-CHLOROACETAMIDE 95.00%
500MG
$ 550.20

Total 3 raw suppliers

Chemical Property of N-(1-Benzyl-pyrrolidin-3-yl)-2-chloro-acetamide

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:252.1029409
Heavy Atom Count:17
Complexity:254

Purity/Quality:

≥95% ^*data from raw suppliers

N-(1-Benzyl-pyrrolidin-3-yl)-2-chloro-acetamide 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CN(CC1NC(=O)CCl)CC2=CC=CC=C2

Technology Process of N-(1-Benzyl-pyrrolidin-3-yl)-2-chloro-acetamide

There total 1 articles about N-(1-Benzyl-pyrrolidin-3-yl)-2-chloro-acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.7%

: 18471-40-4,60652-45-1,114715-38-7,114715-39-8
1-Benzyl-3-aminopyrrolidine

: 79-04-9
chloroacetyl chloride

: 939758-04-0
C₁₃H₁₇ClN₂O

Guidance literature:: In dichloromethane; at 0 - 20 ℃;

Reference yield: 86.2%

: 939758-04-0
C₁₃H₁₇ClN₂O

: 1152838-28-2
C₁₃H₁₉N₃O

Guidance literature:: With ammonia; In methanol; water; at 45 ℃;

Reference yield:

: 939758-04-0
C₁₃H₁₇ClN₂O

: 1196537-76-4
N-{2-[(1-benzylpyrrolidin-3-yl)amino]-2-oxoethyl}-5-formyl-2,4-dimethyl-1H-pyrrole-3-formamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: ammonia / water; methanol / 45 °C

2.1: triethylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / benzotriazol-1-ol / N,N-dimethyl-formamide / 1.5 h / 0 °C

2.2: 20 °C

With ammonia; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; benzotriazol-1-ol; In methanol; water; N,N-dimethyl-formamide;