5-[(S)-1-(4-iodo-5-methoxy-2-nitrophenyl)-2,2-dimethylpropyloxy]methyl-2’-deoxyuridine

Base Information

Chemical Name:5-[(S)-1-(4-iodo-5-methoxy-2-nitrophenyl)-2,2-dimethylpropyloxy]methyl-2’-deoxyuridine
CAS No.:1427311-62-3
Molecular Formula:C₂₂H₂₈IN₃O₉
Molecular Weight:605.384
Hs Code.:

Synonyms:5-[(S)-1-(4-iodo-5-methoxy-2-nitrophenyl)-2,2-dimethylpropyloxy]methyl-2’-deoxyuridine

Suppliers and Price of 5-[(S)-1-(4-iodo-5-methoxy-2-nitrophenyl)-2,2-dimethylpropyloxy]methyl-2’-deoxyuridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5-[(S)-1-(4-iodo-5-methoxy-2-nitrophenyl)-2,2-dimethylpropyloxy]methyl-2’-deoxyuridine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5-[(S)-1-(4-iodo-5-methoxy-2-nitrophenyl)-2,2-dimethylpropyloxy]methyl-2’-deoxyuridine

There total 8 articles about 5-[(S)-1-(4-iodo-5-methoxy-2-nitrophenyl)-2,2-dimethylpropyloxy]methyl-2’-deoxyuridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

: C₃₉H₆₄IN₃O₁₁Si₂

: 1427311-62-3
5-[(S)-1-(4-iodo-5-methoxy-2-nitrophenyl)-2,2-dimethylpropyloxy]methyl-2’-deoxyuridine

Guidance literature:: With ammonium fluoride; In methanol; at 50 ℃; for 12h;

Reference yield:

: 1028383-90-5
N³-tert-butyloxycarbonyl-5-bromomethyl-3',5'-bis-O-tert-butyldimethylsilyl-2'-deoxyuridine

: 1427311-62-3
5-[(S)-1-(4-iodo-5-methoxy-2-nitrophenyl)-2,2-dimethylpropyloxy]methyl-2’-deoxyuridine

Guidance literature:: Multi-step reaction with 2 steps

1: 0.75 h / 110 °C / Inert atmosphere

2: ammonium fluoride / methanol / 12 h / 50 °C

With ammonium fluoride; In methanol;

Reference yield:

: 766-85-8
3-methoxy-1-iodobenzene

: 1427311-62-3
5-[(S)-1-(4-iodo-5-methoxy-2-nitrophenyl)-2,2-dimethylpropyloxy]methyl-2’-deoxyuridine

Guidance literature:: Multi-step reaction with 7 steps

1.1: sodium nitrite; acetic acid; nitric acid / 24 h / 20 °C

1.2: 60 °C

2.1: phenylmagnesium chloride / tetrahydrofuran / 2 h / -40 °C / Inert atmosphere

2.2: 3 h / -30 - 20 °C / Inert atmosphere

2.3: Inert atmosphere

3.1: dmap / dichloromethane / 20 °C / Inert atmosphere

4.1: ethanol / Reflux

5.1: potassium carbonate; methanol / 1 h / Reflux

6.1: 0.75 h / 110 °C / Inert atmosphere

7.1: ammonium fluoride / methanol / 12 h / 50 °C

With methanol; dmap; ammonium fluoride; phenylmagnesium chloride; nitric acid; potassium carbonate; acetic acid; sodium nitrite; In tetrahydrofuran; methanol; ethanol; dichloromethane;