N-{4-nitrophenyl}cyclopropanecarboxamide

Base Information

• Chemical Name: N-{4-nitrophenyl}cyclopropanecarboxamide
• CAS No.: 14372-12-4
• Molecular Formula: C₁₀H₁₀N₂O₃
• Molecular Weight: 206.201
• Mol file: 14372-12-4.mol

Synonyms:cyclopropanecarboxylic acid (4-nitrophenyl)amide

Chemical Property of N-{4-nitrophenyl}cyclopropanecarboxamide

Chemical Property:

Purity/Quality:

N-(4-NITROPHENYL)CYCLOPROPANECARBOXAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-{4-nitrophenyl}cyclopropanecarboxamide

There total 6 articles about N-{4-nitrophenyl}cyclopropanecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

cyclopropanecarboxylic acid chloride (4023-34-1) + 4-nitro-aniline (100-01-6,104810-17-5) → cyclopropanecarboxylic acid (4-nitrophenyl)amide (14372-12-4)

Guidance literature:

With potassium carbonate; In acetonitrile; at 20 ℃; for 2h;

DOI:10.1021/jo0516988

Reference yield: 78.0%

4-nitro-aniline (100-01-6,104810-17-5) + Cyclopropanecarboxaldehyde (1489-69-6) → cyclopropanecarboxylic acid (4-nitrophenyl)amide (14372-12-4)

Guidance literature:

4-nitro-aniline; With tert.-butylnitrite; trimethylsilylazide; In tetrahydrofuran; at 0 ℃;

Cyclopropanecarboxaldehyde; With 3-benzyl-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium chloride; sodium t-butanolate; In tetrahydrofuran; at -25 ℃;

DOI:10.1039/c3cc40452h

Reference yield: 76.0%

N-phenylcyclopropanecarboxamide (2759-52-6) → cyclopropanecarboxylic acid (4-nitrophenyl)amide (14372-12-4) + N-(2-nitrophenyl)cyclopropanecarboxamide (23745-08-6)

Guidance literature:

With tert.-butylnitrite; copper(II) nitrate trihydrate; In acetonitrile; at 80 ℃; for 2h;

DOI:10.1002/ejoc.201403510

upstream raw materials:

cyclopropanecarboxylic acid chloride

4-nitro-aniline

Cyclopropanecarboxaldehyde

4-nitrophenyl azide

Downstream raw materials:

1-(4-nitrophenyl)pyrrolidin-2-one

{triphenylphosphinegold(p-nitrophenyl)carbamoyl}cyclopropane

N-(4-aminophenyl)cyclopropanecarboxamide