4-(Dimethylamino)benzoic acid 2-benzoylhydrazide

Base Information

• Chemical Name: 4-(Dimethylamino)benzoic acid 2-benzoylhydrazide
• CAS No.: 6797-81-5
• Molecular Formula: C₁₆H₁₇N₃O₂
• Molecular Weight: 283.33
• DSSTox Substance ID: DTXSID201237755
• Mol file: 6797-81-5.mol

Synonyms:DTXSID201237755;AKOS034126670;6797-81-5;4-(Dimethylamino)benzoic acid 2-benzoylhydrazide;Z30187136

Chemical Property of 4-(Dimethylamino)benzoic acid 2-benzoylhydrazide

Chemical Property:

• XLogP3: 1.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 283.132076794
• Heavy Atom Count: 21
• Complexity: 357

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CN(C)C1=CC=C(C=C1)C(=O)NNC(=O)C2=CC=CC=C2

Technology Process of 4-(Dimethylamino)benzoic acid 2-benzoylhydrazide

There total 4 articles about 4-(Dimethylamino)benzoic acid 2-benzoylhydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(dimethylamino)benzoyl chloride (4755-50-4) + benzoic acid hydrazide (613-94-5) → 4-dimethylamino-benzoic acid N'-benzoyl-hydrazide (6797-81-5)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃;

DOI:10.1021/jm2013248

Reference yield:

methyl 4-(N,N-dimethylamino)benzoate (1202-25-1) → 4-dimethylamino-benzoic acid N'-benzoyl-hydrazide (6797-81-5)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrazine

2: pyridine / Heating

With pyridine; hydrazine;

DOI:10.1002/mrc.2804

Reference yield:

4-(dimethylamino)benzohydrazide (19353-92-5) + benzoyl chloride (98-88-4) → 4-dimethylamino-benzoic acid N'-benzoyl-hydrazide (6797-81-5)

Guidance literature:

With pyridine; Heating;

DOI:10.1002/mrc.2804

upstream raw materials:

methyl 4-(N,N-dimethylamino)benzoate

4-(dimethylamino)benzohydrazide

benzoyl chloride

4-(dimethylamino)benzoyl chloride

Downstream raw materials:

2-(N,N-dimethyl-4-aminophenyl)-5-phenyl-1,3,4-oxadiazole