5,6,7,8-Tetrahydroquinolin-5-ol

Base Information

Chemical Name:5,6,7,8-Tetrahydroquinolin-5-ol
CAS No.:194151-99-0
Molecular Formula:C₉H₁₁NO
Molecular Weight:149.192
Hs Code.:
DSSTox Substance ID:DTXSID00404726
Mol file:194151-99-0.mol

Synonyms:5,6,7,8-tetrahydroquinolin-5-ol;194151-99-0;5-Hydroxy-5,6,7,8-tetrahydroquinoline;5-Quinolinol, 5,6,7,8-tetrahydro-;SCHEMBL2656448;DTXSID00404726;LANQCUHPUQHIAO-UHFFFAOYSA-N;MFCD01312582;ZB0631;AKOS006278958;5-Hydroxy 5,6,7,8-tetrahydro-quinoline;5-Hydroxy-(5,6,7,8)-tetrahydroquinoline;CS-0213286;FT-0692651;EN300-3457991;Z1198156585

Suppliers and Price of 5,6,7,8-Tetrahydroquinolin-5-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
5,6,7,8-Tetrahydroquinolin-5-ol 97%
1g
$ 389.00

Chemcia Scientific
5,6,7,8-Tetrahydro-quinolin-5-ol 95%
1 G
$ 425.00

American Custom Chemicals Corporation
5-HYDROXY-5,6,7,8-TETRAHYDROQUINOLINE 95.00%
1G
$ 1515.94

Alichem
5-Hydroxy-5,6,7,8-tetrahydroquinoline
1g
$ 446.76

Alichem
5-Hydroxy-5,6,7,8-tetrahydroquinoline
250mg
$ 171.50

Total 5 raw suppliers

Chemical Property of 5,6,7,8-Tetrahydroquinolin-5-ol

Chemical Property:

Vapor Pressure:0.00103mmHg at 25°C
Refractive Index:1.59
Boiling Point:289.2°C at 760 mmHg
Flash Point:128.7°C
PSA：33.12000
Density:1.179g/cm³
LogP:1.45130
XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:149.084063974
Heavy Atom Count:11
Complexity:138

Purity/Quality:

90% ^*data from raw suppliers

5,6,7,8-Tetrahydroquinolin-5-ol 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(C2=C(C1)N=CC=C2)O

Technology Process of 5,6,7,8-Tetrahydroquinolin-5-ol

There total 4 articles about 5,6,7,8-Tetrahydroquinolin-5-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 53400-41-2
5,6,7,8-tetrahydroquinolin-5-one

: 194151-99-0
5,6,7,8-tetrahydroquinolin-5-ol

Guidance literature:: With sodium tetrahydroborate; In methanol;
DOI:10.1021/jo00220a057

Reference yield:

: 1-(2-bromopyridin-3-yl)but-3-en-1-ol

: 194151-99-0
5,6,7,8-tetrahydroquinolin-5-ol

: C₉H₁₁NO

Guidance literature:: With diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; 2,4,6-tris(diphenylamino)-5-fluoroisophthalonitrile; In water monomer; acetonitrile; at 23 ℃; for 16h; Overall yield = 53 percent; Overall yield = 0.02 g; regioselective reaction; Inert atmosphere; Sealed tube; Irradiation;
DOI:10.1021/jacs.2c00192

Reference yield:

: 5220-49-5
3-amino-cyclohex-2-enone

: 194151-99-0
5,6,7,8-tetrahydroquinolin-5-ol

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) DMF, RT, 48 h, 2.) 140 deg C, 5 min

2: 91 percent / NaBH₄ / methanol / 18 h / 0 - 20 °C

With sodium tetrahydroborate; In methanol;
DOI:10.1021/jm9800797