((1S,2R,5R)-2-Isopropenyl-5-methyl-cyclohexyl)-acetic acid methyl ester

Base Information

• Chemical Name: ((1S,2R,5R)-2-Isopropenyl-5-methyl-cyclohexyl)-acetic acid methyl ester
• CAS No.: 114032-14-3
• Molecular Formula: C₁₃H₂₂O₂
• Molecular Weight: 210.316
• Mol file: 114032-14-3.mol

Synonyms:((1S,2R,5R)-2-Isopropenyl-5-methyl-cyclohexyl)-acetic acid methyl ester

Chemical Property of ((1S,2R,5R)-2-Isopropenyl-5-methyl-cyclohexyl)-acetic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ((1S,2R,5R)-2-Isopropenyl-5-methyl-cyclohexyl)-acetic acid methyl ester

There total 3 articles about ((1S,2R,5R)-2-Isopropenyl-5-methyl-cyclohexyl)-acetic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

dimethyl (1'R,2'R,5'R)-2-(2'-isopropenyl-5'-methylcyclohex-1'-yl)-propane-1,3-dioate (106431-81-6) → ((1S,2R,5R)-2-Isopropenyl-5-methyl-cyclohexyl)-acetic acid methyl ester (114032-14-3)

Guidance literature:

With dimethyl sulfoxide; sodium chloride; In water; at 150 ℃; for 4h;

Reference yield:

(S)-Citronellal (5949-05-3) → ((1R,2S,5S)-2-Isopropenyl-5-methyl-cyclohexyl)-acetic acid methyl ester (91975-82-5,114032-14-3)

Guidance literature:

Multi-step reaction with 3 steps

1: pyridinium acetate / CH₂Cl₂

2: FeCl₃/Al₂O₃

3: NaCl,Me₂SO / H₂O

With aluminum oxide; pyridinium acetate; iron(III) chloride; dimethyl sulfoxide; sodium chloride; In dichloromethane; water;

Reference yield:

2-((S)-3,7-Dimethyl-oct-6-enylidene)-malonic acid dimethyl ester (130451-44-4) → ((1R,2S,5S)-2-Isopropenyl-5-methyl-cyclohexyl)-acetic acid methyl ester (91975-82-5,114032-14-3)

Guidance literature:

Multi-step reaction with 2 steps

1: FeCl₃/Al₂O₃

2: NaCl,Me₂SO / H₂O

With aluminum oxide; iron(III) chloride; dimethyl sulfoxide; sodium chloride; In water;

upstream raw materials:

(S)-Citronellal

2-((S)-3,7-Dimethyl-oct-6-enylidene)-malonic acid dimethyl ester

dimethyl (1'R,2'R,5'R)-2-(2'-isopropenyl-5'-methylcyclohex-1'-yl)-propane-1,3-dioate

Downstream raw materials:

{(1S,2R,5R)-5-Methyl-2-[1-methylene-3-(toluene-4-sulfonyloxy)-propyl]-cyclohexyl}-acetic acid methyl ester

[(1S,2R,5R)-2-(3-Iodo-1-methylene-propyl)-5-methyl-cyclohexyl]-acetic acid methyl ester

C₁₃H₂₁N

C₂₁H₂₈O₄