1H-Pyrido[3,4-b][1,4]oxazin-2(3H)-one

Base Information

Chemical Name:1H-Pyrido[3,4-b][1,4]oxazin-2(3H)-one
CAS No.:194022-44-1
Molecular Formula:C7H6 N2 O2
Molecular Weight:150.137
Hs Code.:2934999090
European Community (EC) Number:897-523-7
DSSTox Substance ID:DTXSID00597561
Wikidata:Q82493153
Mol file:194022-44-1.mol

Synonyms:1H-Pyrido[3,4-b][1,4]oxazin-2(3H)-one;194022-44-1;1H-pyrido[3,4-b][1,4]oxazin-2-one;1H-Pyrido[3,4-b][1,4]oxazin-2(3H)-one(9CI);SCHEMBL1190878;DTXSID00597561;VFLQBRXQPWSXGJ-UHFFFAOYSA-N;MFCD18809867;AKOS023833183;AS-42216;1H-pyrido[3,4-b][1,4]-oxazin-2-one;DB-259660;CS-0312233;1H,2H,3H-pyrido[3,4-b][1,4]oxazin-2-one;1H-pyrido-[3,4-b][1,4]oxazine-2-(3H)one;1H,3H-PYRIDO[3,4-B][1,4]OXAZIN-2-ONE

Suppliers and Price of 1H-Pyrido[3,4-b][1,4]oxazin-2(3H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1H-Pyrido[3,4-B][1,4]oxazin-2(3H)-one
100mg
$ 310.00

TRC
1H-Pyrido[3,4-B][1,4]oxazin-2(3H)-one
50mg
$ 200.00

Crysdot
1H-Pyrido[3,4-b][1,4]oxazin-2(3H)-one 95+%
1g
$ 709.00

Total 7 raw suppliers

Chemical Property of 1H-Pyrido[3,4-b][1,4]oxazin-2(3H)-one

Chemical Property:

PSA：51.22000
LogP:0.55050
XLogP3:-0.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:150.042927438
Heavy Atom Count:11
Complexity:172

Purity/Quality:

97% ^*data from raw suppliers

1H-Pyrido[3,4-B][1,4]oxazin-2(3H)-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(=O)NC2=C(O1)C=NC=C2

Technology Process of 1H-Pyrido[3,4-b][1,4]oxazin-2(3H)-one

There total 3 articles about 1H-Pyrido[3,4-b][1,4]oxazin-2(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 52334-53-9
4-amino-3-hydroxy pyridine

: 79-04-9
chloroacetyl chloride

: 194022-44-1
1H-Pyrido[3,4-b][1,4]oxazine-2-(3H)one

Guidance literature:: 4-amino-3-hydroxy pyridine; chloroacetyl chloride; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h; Inert atmosphere;

With potassium carbonate; In N,N-dimethyl-formamide; at 20 - 100 ℃;

Reference yield:

: 194022-43-0
2-chloro-N-(3-hydroxy-4-pyridyl)acetamide

: 194022-44-1
1H-Pyrido[3,4-b][1,4]oxazine-2-(3H)one

Guidance literature:: With potassium carbonate; In methanol; water; ethyl acetate;

Reference yield:

: 52334-53-9
4-amino-3-hydroxy pyridine

: 194022-44-1
1H-Pyrido[3,4-b][1,4]oxazine-2-(3H)one

Guidance literature:: Multi-step reaction with 2 steps

1: 2 h / 80 °C

2: potassium carbonate / water / 16 h / 20 °C

With potassium carbonate; In water;