2-dimethylamino-5-[1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl]benzenesulphonamide

Base Information

• Chemical Name: 2-dimethylamino-5-[1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl]benzenesulphonamide
• CAS No.: 68504-56-3
• Molecular Formula: C₂₀H₂₉N₃O₃S
• Molecular Weight: 391.535
• Mol file: 68504-56-3.mol

Synonyms:2-dimethylamino-5-[1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl]benzenesulphonamide

Chemical Property of 2-dimethylamino-5-[1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl]benzenesulphonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-dimethylamino-5-[1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl]benzenesulphonamide

There total 4 articles about 2-dimethylamino-5-[1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl]benzenesulphonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-Phenyl-2-butanone (2550-26-7) + 2-dimethylamino-5-[1-hydroxy-2-[bis(phenylmethyl)amino]ethyl]benzenesulphonamide (68504-90-5) → 2-dimethylamino-5-[1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl]benzenesulphonamide (68504-56-3)

Guidance literature:

With hydrogen; palladium on activated charcoal; platinum on activated charcoal; In ethanol; under 2589 Torr; Ambient temperature;

Reference yield:

4'-chloro-3'-sulfamoyl-acetophenone (2350-44-9) → 2-dimethylamino-5-[1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl]benzenesulphonamide (68504-56-3)

Guidance literature:

Multi-step reaction with 4 steps

1: ethanol

2: hydrogen bromide; bromine / chloroform; acetic acid

3: (i) methyloxirane, MeCOEt, (ii) NaBH₄, EtOH

4: hydrogen / palladium on activated charcoal; platinum on activated charcoal / ethanol / 2589 Torr / Ambient temperature

With hydrogen bromide; hydrogen; bromine; palladium on activated charcoal; platinum on activated charcoal; In ethanol; chloroform; acetic acid;

Reference yield:

5-acetyl-2-dimethylaminobenzenesulphonamide (68504-88-1) → 2-dimethylamino-5-[1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl]benzenesulphonamide (68504-56-3)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrogen bromide; bromine / chloroform; acetic acid

2: (i) methyloxirane, MeCOEt, (ii) NaBH₄, EtOH

3: hydrogen / palladium on activated charcoal; platinum on activated charcoal / ethanol / 2589 Torr / Ambient temperature

With hydrogen bromide; hydrogen; bromine; palladium on activated charcoal; platinum on activated charcoal; In ethanol; chloroform; acetic acid;

upstream raw materials:

4-Phenyl-2-butanone

2-dimethylamino-5-[1-hydroxy-2-[bis(phenylmethyl)amino]ethyl]benzenesulphonamide

4'-chloro-3'-sulfamoyl-acetophenone

5-acetyl-2-dimethylaminobenzenesulphonamide