5-acetyl-2-dimethylaminobenzenesulphonamide

Base Information

• Chemical Name: 5-acetyl-2-dimethylaminobenzenesulphonamide
• CAS No.: 68504-88-1
• Molecular Formula: C₁₀H₁₄N₂O₃S
• Molecular Weight: 242.299
• Mol file: 68504-88-1.mol

Synonyms:5-acetyl-2-dimethylaminobenzenesulphonamide

Chemical Property of 5-acetyl-2-dimethylaminobenzenesulphonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-acetyl-2-dimethylaminobenzenesulphonamide

There total 1 articles about 5-acetyl-2-dimethylaminobenzenesulphonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4'-chloro-3'-sulfamoyl-acetophenone (2350-44-9) → 5-acetyl-2-dimethylaminobenzenesulphonamide (68504-88-1)

Guidance literature:

With dimethyl amine; In ethanol;

Reference yield:

5-acetyl-2-dimethylaminobenzenesulphonamide (68504-88-1) → 5-bromoacetyl-2-dimethylaminobenzenesulphonamide (68504-89-2)

Guidance literature:

With hydrogen bromide; bromine; In chloroform; acetic acid;

Reference yield:

5-acetyl-2-dimethylaminobenzenesulphonamide (68504-88-1) → 2-dimethylamino-5-[1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl]benzenesulphonamide (68504-56-3)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrogen bromide; bromine / chloroform; acetic acid

2: (i) methyloxirane, MeCOEt, (ii) NaBH₄, EtOH

3: hydrogen / palladium on activated charcoal; platinum on activated charcoal / ethanol / 2589 Torr / Ambient temperature

With hydrogen bromide; hydrogen; bromine; palladium on activated charcoal; platinum on activated charcoal; In ethanol; chloroform; acetic acid;

upstream raw materials:

4'-chloro-3'-sulfamoyl-acetophenone

Downstream raw materials:

5-bromoacetyl-2-dimethylaminobenzenesulphonamide

2-dimethylamino-5-[1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl]benzenesulphonamide

2-dimethylamino-5-[1-hydroxy-2-[bis(phenylmethyl)amino]ethyl]benzenesulphonamide