2,3-Dihydrofuro[2,3-c]pyridine-5-carbonitrile

Base Information

Chemical Name:2,3-Dihydrofuro[2,3-c]pyridine-5-carbonitrile
CAS No.:193605-62-8
Molecular Formula:C₈H₆N₂O
Molecular Weight:146.148
Hs Code.:
DSSTox Substance ID:DTXSID701238891
Mol file:193605-62-8.mol

Synonyms:193605-62-8;2,3-dihydrofuro[2,3-c]pyridine-5-carbonitrile;FURO[2,3-C]PYRIDINE-5-CARBONITRILE, 2,3-DIHYDRO- (9CI);DTXSID701238891;Furo[2,3-c]pyridine-5-carbonitrile, 2,3-dihydro-

Suppliers and Price of 2,3-Dihydrofuro[2,3-c]pyridine-5-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 2,3-Dihydrofuro[2,3-c]pyridine-5-carbonitrile

Chemical Property:

PSA：45.91000
LogP:0.88818
XLogP3:0.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:146.048012819
Heavy Atom Count:11
Complexity:196

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COC2=CN=C(C=C21)C#N

Technology Process of 2,3-Dihydrofuro[2,3-c]pyridine-5-carbonitrile

There total 3 articles about 2,3-Dihydrofuro[2,3-c]pyridine-5-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

: 7677-24-9
trimethylsilyl cyanide

: 193605-32-2
2,3-dihydrofuro[2,3-c]pyridine N-oxide

: 193605-63-9
7-cyano-2,3-dihydrofuro[2,3-c]pyridine

: 193605-62-8
5-cyano-2,3-dihydrofuro[2,3-c]pyridine

Guidance literature:: With triethylamine; In acetonitrile; for 20h; Heating;
DOI:10.1002/jhet.5570340336

Reference yield:

: 19539-50-5
furo<2,3-c>pyridine

: 193605-62-8
5-cyano-2,3-dihydrofuro[2,3-c]pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: 95 percent / H₂, AcOH / 5percent Pd/C / methanol / 25 h / Ambient temperature

2: 81 percent / m-chloroperbenzoic acid / CHCl₃ / 18 h / Ambient temperature

3: 34 percent / Et₃N / acetonitrile / 20 h / Heating

With hydrogen; acetic acid; triethylamine; 3-chloro-benzenecarboperoxoic acid; palladium on activated charcoal; In methanol; chloroform; acetonitrile;
DOI:10.1002/jhet.5570340336

Reference yield:

: 117103-45-4
2,3-dihydrofuro<2,3-c>pyridine

: 193605-62-8
5-cyano-2,3-dihydrofuro[2,3-c]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / m-chloroperbenzoic acid / CHCl₃ / 18 h / Ambient temperature

2: 34 percent / Et₃N / acetonitrile / 20 h / Heating

With triethylamine; 3-chloro-benzenecarboperoxoic acid; In chloroform; acetonitrile;
DOI:10.1002/jhet.5570340336