Benzene, 1,3-bis(diisopropylphosphinomethyl)-

Base Information

• Chemical Name: Benzene, 1,3-bis(diisopropylphosphinomethyl)-
• CAS No.: 193084-64-9
• Molecular Formula: C20H36 P2
• Molecular Weight: 338.453
• Mol file: 193084-64-9.mol

Synonyms:Phosphine,[1,3-phenylenebis(methylene)]bis[bis(1-methylethyl)- (9CI); 1,3-Bis(diisopropylphosphinomethyl)benzene

Chemical Property of Benzene, 1,3-bis(diisopropylphosphinomethyl)-

Chemical Property:

• PSA: 27.18000
• LogP: 7.28400

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzene, 1,3-bis(diisopropylphosphinomethyl)-

There total 5 articles about Benzene, 1,3-bis(diisopropylphosphinomethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

Chlorodiisopropylphosphane (40244-90-4) + 1,3-bis-(bromomethyl)benzene (626-15-3) → 1,3-bis[(diisopropyl-phosphanyl)-methyl]benzene (193084-64-9)

Guidance literature:

Chlorodiisopropylphosphane; 1,3-bis-(bromomethyl)benzene; In acetonitrile; at 100 ℃; for 15h; Inert atmosphere; Glovebox;

With magnesium; In acetonitrile; at 0 - 20 ℃; Inert atmosphere; Glovebox;

DOI:10.1021/acs.oprd.1c00205

Reference yield: 70.0%

di-isopropylphosphine (20491-53-6) + 1,3-bis-(bromomethyl)benzene (626-15-3) → 1,3-bis[(diisopropyl-phosphanyl)-methyl]benzene (193084-64-9)

Guidance literature:

di-isopropylphosphine; 1,3-bis-(bromomethyl)benzene; In acetone; for 24h; Glovebox; Reflux; Inert atmosphere;

With triethylamine; In benzene; at 20 ℃; for 60h;

Reference yield: 70.0%

di-isopropylphosphine (20491-53-6) + dibromo-m-xylene (90434-19-8) → 1,3-bis[(diisopropyl-phosphanyl)-methyl]benzene (193084-64-9)

Guidance literature:

With triethylamine; In tetrahydrofuran; for 24h; Glovebox; Inert atmosphere; Reflux;

DOI:10.1021/jacs.5b05313

upstream raw materials:

di-isopropylphosphine

1,3-bis-(bromomethyl)benzene

1,3-bis((diisopropylphosphaneyl)oxy)benzene

(2,6-bis(diisopropylphosphinomethyl)phenyl)bromonickel

Downstream raw materials:

hydrogenchloride

(^iPrPCP)RuCl(PPh₃)

(2,6-bis[(diisopropylphosphino-κP)methyl]phenyl-κC)chloro(triphenylphosphine)ruthenium

(PCP)Pt[C(N₂)Ph]