2-Benzothiazolamine,6-pentyl-(9CI)

Base Information

• Chemical Name: 2-Benzothiazolamine,6-pentyl-(9CI)
• CAS No.: 191719-16-1
• Molecular Formula: C₁₂H₁₆N₂S
• Molecular Weight: 220.338
• Mol file: 191719-16-1.mol

Synonyms:2-Amino-6-pentylbenzothiazole

Chemical Property of 2-Benzothiazolamine,6-pentyl-(9CI)

Chemical Property:

• PSA: 67.88000
• LogP: 3.54130

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Benzothiazolamine,6-pentyl-(9CI)

There total 1 articles about 2-Benzothiazolamine,6-pentyl-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

4-pentylaniline (33228-44-3) + potassium thioacyanate (333-20-0) → 6-pentyl-benzothiazol-2-ylamine (191719-16-1)

Guidance literature:

With bromine; acetic acid; for 21h; Ambient temperature;

DOI:10.1021/jm980202u

Reference yield: 60.0%

6-pentyl-benzothiazol-2-ylamine (191719-16-1) → C22H32N2S2

Guidance literature:

With potassium hydroxide; In 1,2-dimethoxyethane; at 120 ℃; for 20h; Inert atmosphere;

upstream raw materials:

4-pentylaniline

potassium thioacyanate

Refernces

• 1、 Jimonet, Patrick,Audiau, Fran?ois,Barreau, Michel,Blanchard, Jean-Charles,Boireau, Alain,Bour, Yvette,Coléno, Marie-Annick,Doble, Adam,Doerflinger, Gilles,Do Huu, Claudine,Donat, Marie-Hélène,Duchesne, Jean Marie,Ganil, Pierre,Guérémy, Claude,Honoré, Eliane,Just, Bernard,Kerphirique, Roselyne,Gontier, Sylvie,Hubert, Philippe,Laduron, Pierre M.,Blevec, Joseph Le,Meunier, Mireille,Miquet, Jean-Marie,Nemecek, Conception,Pasquet, Martine,Piot, Odile,Pratt, Jeremy,Rataud, Jean,Reibaud, Michel,Stutzmann, Jean-Marie,Mignani, Serge. "Riluzole series. synthesis and in vivo 'antiglutamate' activity of 6- substituted-2-benzothiazolamines and 3-substituted-2-imino-benzothiazolines". . p. 2828 - 2843. Retrieved 2007/10/03.