C₄₉H₃₃N₃O

Base Information

• Chemical Name: C₄₉H₃₃N₃O
• CAS No.: 1259882-74-0
• Molecular Formula: C₄₉H₃₃N₃O
• Molecular Weight: 679.821
• Mol file: 1259882-74-0.mol

Synonyms:C₄₉H₃₃N₃O

Chemical Property of C₄₉H₃₃N₃O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₉H₃₃N₃O

There total 10 articles about C₄₉H₃₃N₃O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

1-phenyl-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-phenyl]-1H-benzo[d]imidazole (1146340-38-6) + 9-(4-(4'-bromobiphenyl-4-yloxy)phenyl)-9H-carbazole (1259882-70-6) → C49H33N3O (1259882-74-0)

Guidance literature:

With potassium fluoride; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In N,N-dimethyl-formamide; at 80 ℃; Inert atmosphere;

Reference yield:

4-chlorobenzoyl chloride (586-75-4) → C49H33N3O (1259882-74-0)

Guidance literature:

Multi-step reaction with 4 steps

1: triethylamine / dichloromethane / 20 °C

2: trichlorophosphate / 1,4-dioxane / 100 °C

3: potassium acetate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane / 80 °C / Inert atmosphere

4: potassium fluoride / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / N,N-dimethyl-formamide / 80 °C / Inert atmosphere

With potassium fluoride; potassium acetate; triethylamine; trichlorophosphate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In 1,4-dioxane; dichloromethane; N,N-dimethyl-formamide;

Reference yield:

2-(4-bromophenyl)-1-phenyl-1H-benzimidazole (2620-76-0) → C49H33N3O (1259882-74-0)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium acetate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane / 80 °C / Inert atmosphere

2: potassium fluoride / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / N,N-dimethyl-formamide / 80 °C / Inert atmosphere

With potassium fluoride; potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In 1,4-dioxane; N,N-dimethyl-formamide;

upstream raw materials:

4-chlorobenzoyl chloride

9H-carbazole

para-iodoanisole

9-(4-methoxyphenyl)-9H-carbazole

Refernces

• 1、 -. "EMISSIVE ARYL-HETEROARYL COMPOUNDS". . . Retrieved 2011/02/24.