2,3,4,6-tetra-O-benzyl-1,5-dideoxy-1-[(2',2'-dimethoxyethyl)imino]-1,5-imino-D-glucitol

Base Information

• Chemical Name: 2,3,4,6-tetra-O-benzyl-1,5-dideoxy-1-[(2',2'-dimethoxyethyl)imino]-1,5-imino-D-glucitol
• CAS No.: 191863-31-7
• Molecular Formula: C₃₈H₄₄N₂O₆
• Molecular Weight: 624.777
• Mol file: 191863-31-7.mol

Synonyms:2,3,4,6-tetra-O-benzyl-1,5-dideoxy-1-[(2',2'-dimethoxyethyl)imino]-1,5-imino-D-glucitol

Chemical Property of 2,3,4,6-tetra-O-benzyl-1,5-dideoxy-1-[(2',2'-dimethoxyethyl)imino]-1,5-imino-D-glucitol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3,4,6-tetra-O-benzyl-1,5-dideoxy-1-[(2',2'-dimethoxyethyl)imino]-1,5-imino-D-glucitol

There total 14 articles about 2,3,4,6-tetra-O-benzyl-1,5-dideoxy-1-[(2',2'-dimethoxyethyl)imino]-1,5-imino-D-glucitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2,3,4,6-tetra-O-benzyl-D-glucono-δ-thiolactam (153996-70-4) + 2,2-dimethoxyethylamine (22483-09-6) → (2,2-Dimethoxy-ethyl)-[(3S,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-piperidin-(2Z)-ylidene]-amine (191863-31-7)

Guidance literature:

With mercury(II) diacetate; In tetrahydrofuran; at 5 ℃; for 0.833333h;

DOI:10.1002/hlca.19970800329

Reference yield:

2,3,4,6-tetra-O-benzyl-D-glucono-δ-thiolactam (153996-70-4) + 2,2-dimethoxyethylamine (22483-09-6) → 2,3,4,6-tetra-O-benzyl-1,5-dideoxy-1-[(2',2'-dimethoxyethyl)imino]-1,5-imino-D-glucitol (191863-31-7)

Guidance literature:

With mercury(II) diacetate; In tetrahydrofuran; at 0 ℃; for 0.833333h;

DOI:10.1016/j.bmc.2011.02.043

Reference yield:

(2,2-Dimethoxy-ethyl)-[(3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-piperidin-(2Z)-ylidene]-amine (191863-32-8) → (2,2-Dimethoxy-ethyl)-[(3S,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-piperidin-(2Z)-ylidene]-amine (191863-31-7)

Guidance literature:

With toluene-4-sulfonic acid; In chloroform-d1; at 25 ℃; for 168h;

DOI:10.1002/hlca.19970800329

upstream raw materials:

2,3,4,6-tetra-O-benzyl-D-glucono-δ-thiolactam

2,2-dimethoxyethylamine

(2,2-Dimethoxy-ethyl)-[(3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-piperidin-(2Z)-ylidene]-amine

2,3,4,6-Tetra-O-benzyl-D-glucopyranose

Downstream raw materials:

(2,2-Dimethoxy-ethyl)-[(3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-piperidin-(2Z)-ylidene]-amine

(5R,6R,7S,8S)-6,7,8-tris(benzyloxy)-5-[(benzyloxy)methyl]-2-(3,3-dimethylbut-1-ynyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine

(5R,6R,7S,8S)-6,7,8-tris(benzyloxy)-5-[(benzyloxy)methyl]-2-(2-(4-methylphenyl)ethynyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine

(5R,6R,7S,8S)-6,7,8-tris(benzyloxy)-5-[(benzyloxy)methyl]-2-(2-(4-methoxyphenyl)ethynyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine