(R)-3-(Tosyloxymethyl)-N-Boc-piperidine

Base Information

Chemical Name:(R)-3-(Tosyloxymethyl)-N-Boc-piperidine
CAS No.:191092-08-7
Molecular Formula:C18H27 N O5 S
Molecular Weight:369.482
Hs Code.:
Mol file:191092-08-7.mol

Synonyms:1-Piperidinecarboxylicacid, 3-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-, 1,1-dimethylethyl ester,(S)-; (S)-1-tert-Butoxycarbonyl-3-(p-toluenesulfonyloxymethyl)piperidine

Suppliers and Price of (R)-3-(Tosyloxymethyl)-N-Boc-piperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 0 raw suppliers

Chemical Property of (R)-3-(Tosyloxymethyl)-N-Boc-piperidine

Chemical Property:

PSA：81.29000
LogP:4.36610

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (R)-3-(Tosyloxymethyl)-N-Boc-piperidine

There total 5 articles about (R)-3-(Tosyloxymethyl)-N-Boc-piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 140695-84-7
tert-butyl (3S)-3-(hydroxymethyl)piperidine-1-carboxylate

: 98-59-9
p-toluenesulfonyl chloride

: 191092-08-7
tert-butyl (3S)-3-[[(4-methylbenzenesulfonyl)oxy]methyl]piperidine-1-carboxylate

Guidance literature:: In pyridine; at 0 ℃;

Reference yield: 96.0%

: 191092-08-7
tert-butyl (3S)-3-[[(4-methylbenzenesulfonyl)oxy]methyl]piperidine-1-carboxylate

Guidance literature:

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 191092-08-7
tert-butyl (3S)-3-[[(4-methylbenzenesulfonyl)oxy]methyl]piperidine-1-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / dichloromethane / 3 h / 20 °C

2: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 0 - 20 °C

3: dmap; triethylamine / dichloromethane / 3 h / 20 °C

With dmap; lithium aluminium tetrahydride; triethylamine; In tetrahydrofuran; dichloromethane;