N,N'-didodecyl-4-[3-(dodecylamino)-3-oxopropyl]-4-{[(4-ethynylphenyl)carbonyl]amino}heptanediamide

Base Information

Chemical Name:N,N'-didodecyl-4-[3-(dodecylamino)-3-oxopropyl]-4-{[(4-ethynylphenyl)carbonyl]amino}heptanediamide
CAS No.:883700-08-1
Molecular Formula:C₅₅H₉₆N₄O₄
Molecular Weight:877.392
Hs Code.:

Synonyms:N,N'-didodecyl-4-[3-(dodecylamino)-3-oxopropyl]-4-{[(4-ethynylphenyl)carbonyl]amino}heptanediamide

Suppliers and Price of N,N'-didodecyl-4-[3-(dodecylamino)-3-oxopropyl]-4-{[(4-ethynylphenyl)carbonyl]amino}heptanediamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N,N'-didodecyl-4-[3-(dodecylamino)-3-oxopropyl]-4-{[(4-ethynylphenyl)carbonyl]amino}heptanediamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N,N'-didodecyl-4-[3-(dodecylamino)-3-oxopropyl]-4-{[(4-ethynylphenyl)carbonyl]amino}heptanediamide

There total 4 articles about N,N'-didodecyl-4-[3-(dodecylamino)-3-oxopropyl]-4-{[(4-ethynylphenyl)carbonyl]amino}heptanediamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 883700-01-4
N,N'-didodecyl-4-[3-(dodecylamino)-3-oxopropyl]-4-[({4-[(trimethylsilyl)ethynyl]phenyl}carbonyl)amino]heptanediamide

: 883700-08-1
N,N'-didodecyl-4-[3-(dodecylamino)-3-oxopropyl]-4-{[(4-ethynylphenyl)carbonyl]amino}heptanediamide

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 0.5h;
DOI:10.1039/b518174g

Reference yield:

: 883699-81-8
N,N'-didodecyl-4-[3-(dodecylamino)-3-oxopropyl]-4-nitroheptanediamide

: 883700-08-1
N,N'-didodecyl-4-[3-(dodecylamino)-3-oxopropyl]-4-{[(4-ethynylphenyl)carbonyl]amino}heptanediamide

Guidance literature:: Multi-step reaction with 4 steps

1: H₂ / Raney-Ni / ethanol / 48 h / 40 - 50 °C / 4500.36 Torr

2: Et₃N / CH₂Cl₂ / 3 h / 20 °C

3: 978 mg / i-Pr₂NH; CuI; (n-Bu)4NBr / [Pd(PPh₃)2Cl₂] / tetrahydrofuran / 24 h / 20 °C

4: 93 percent / aq. tetrabutylammonium fluoride / tetrahydrofuran / 0.5 h / 20 °C

With copper(l) iodide; tetrabutyl ammonium fluoride; tetrabutylammomium bromide; hydrogen; triethylamine; diisopropylamine; bis-triphenylphosphine-palladium(II) chloride; nickel; In tetrahydrofuran; ethanol; dichloromethane;
DOI:10.1039/b518174g

Reference yield:

: 883699-95-4
N,N'-didodecyl-4-[3-(dodecylamino)-3-oxopropyl]-4-{[(4-iodophenyl)carbonyl]amino}heptanediamide

: 883700-08-1
N,N'-didodecyl-4-[3-(dodecylamino)-3-oxopropyl]-4-{[(4-ethynylphenyl)carbonyl]amino}heptanediamide

Guidance literature:: Multi-step reaction with 2 steps

1: 978 mg / i-Pr₂NH; CuI; (n-Bu)4NBr / [Pd(PPh₃)2Cl₂] / tetrahydrofuran / 24 h / 20 °C

2: 93 percent / aq. tetrabutylammonium fluoride / tetrahydrofuran / 0.5 h / 20 °C

With copper(l) iodide; tetrabutyl ammonium fluoride; tetrabutylammomium bromide; diisopropylamine; bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran;
DOI:10.1039/b518174g