(2*,4R,5S)-methyl N-tert-butoxycarbonyl-2-(4'-methoxy)phenyl-4-phenyl-1,3-oxazolidine-5-methionate

Base Information

Chemical Name:(2*,4R,5S)-methyl N-tert-butoxycarbonyl-2-(4'-methoxy)phenyl-4-phenyl-1,3-oxazolidine-5-methionate
CAS No.:859498-33-2
Molecular Formula:C₂₃H₂₇NO₆
Molecular Weight:413.47
Hs Code.:

Synonyms:(2*,4R,5S)-methyl N-tert-butoxycarbonyl-2-(4'-methoxy)phenyl-4-phenyl-1,3-oxazolidine-5-methionate

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Chemical Property of (2*,4R,5S)-methyl N-tert-butoxycarbonyl-2-(4'-methoxy)phenyl-4-phenyl-1,3-oxazolidine-5-methionate

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Technology Process of (2*,4R,5S)-methyl N-tert-butoxycarbonyl-2-(4'-methoxy)phenyl-4-phenyl-1,3-oxazolidine-5-methionate

There total 3 articles about (2*,4R,5S)-methyl N-tert-butoxycarbonyl-2-(4'-methoxy)phenyl-4-phenyl-1,3-oxazolidine-5-methionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 123-11-5
4-methoxy-benzaldehyde

: 161759-90-6
(+)-(2S,3R)-methyl 3-(tert-butoxycarbonylamino)-2-hydroxy-3-phenylpropanoate

: 859498-33-2,153652-75-6
(2*,4R,5S)-methyl N-tert-butoxycarbonyl-2-(4'-methoxy)phenyl-4-phenyl-1,3-oxazolidine-5-methionate

Guidance literature:: With pyridinium p-toluenesulfonate; In toluene;
DOI:10.1002/jhet.5570420430

Reference yield:

: (3S,4R)-3-hydroxy-4-(2'-chlorophenyl)-2-(α-phenylethyl)azetidinone

: 859498-33-2,153652-75-6
(2*,4R,5S)-methyl N-tert-butoxycarbonyl-2-(4'-methoxy)phenyl-4-phenyl-1,3-oxazolidine-5-methionate

Guidance literature:: Multi-step reaction with 3 steps

1.1: HCl / methanol

1.2: 46.5 percent / H₂ / Pd/C

2.1: 91 percent / PPTS / toluene

With hydrogenchloride; pyridinium p-toluenesulfonate; In methanol; toluene;
DOI:10.1002/jhet.5570420430

Reference yield:

: 322407-45-4
(+)-(2S,3R)-methyl 3-amino-2-hydroxy-3-phenylpropanoate

: 859498-33-2,153652-75-6
(2*,4R,5S)-methyl N-tert-butoxycarbonyl-2-(4'-methoxy)phenyl-4-phenyl-1,3-oxazolidine-5-methionate

Guidance literature:: Multi-step reaction with 2 steps

1: 91 percent / PPTS / toluene

With pyridinium p-toluenesulfonate; In toluene;
DOI:10.1002/jhet.5570420430