6-METHYL-2-PHENYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID

Base Information

• Chemical Name: 6-METHYL-2-PHENYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID
• CAS No.: 123533-42-6
• Molecular Formula: C₁₅H₁₂N₂O₂
• Molecular Weight: 252.272
• Hs Code.: 2933399990
• Mol file: 123533-42-6.mol

Synonyms:6-Methyl-2-phenyl-imidazo[1,2-a]pyridine-3-carboxylic acid

Chemical Property of 6-METHYL-2-PHENYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

6-Methyl-2-phenylimidazo[1,2-a]pyridine-3-carboxylicAcid ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

Useful:

Technology Process of 6-METHYL-2-PHENYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID

There total 3 articles about 6-METHYL-2-PHENYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

ethyl 6-methyl-2-phenylimidazo[1,2-a]pyridine-3-carboxylate (127801-87-0) → 6-Methyl-2-phenyl-imidazo[1,2-a]pyridine-3-carboxylic acid (123533-42-6)

Guidance literature:

With sodium hydroxide; In ethanol; at 60 ℃; for 1h;

DOI:10.1002/jhet.5570260664

Reference yield:

(5-methyl-pyridin-2-yl)amine (1603-41-4) → 6-Methyl-2-phenyl-imidazo[1,2-a]pyridine-3-carboxylic acid (123533-42-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 55 percent / ethanol / Heating

2: 60 percent / aq. sodium hydroxide / aq. ethanol / 1 h / 60 °C

With sodium hydroxide; In ethanol;

DOI:10.1002/jhet.5570260664

Reference yield:

ethyl 2-bromo-3-oxo-3-phenylpropionate (55919-47-6) → 6-Methyl-2-phenyl-imidazo[1,2-a]pyridine-3-carboxylic acid (123533-42-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 55 percent / ethanol / Heating

2: 60 percent / aq. sodium hydroxide / aq. ethanol / 1 h / 60 °C

With sodium hydroxide; In ethanol;

DOI:10.1002/jhet.5570260664

upstream raw materials:

ethyl 6-methyl-2-phenylimidazo[1,2-a]pyridine-3-carboxylate

(5-methyl-pyridin-2-yl)amine

ethyl 2-bromo-3-oxo-3-phenylpropionate

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