127801-87-0

Basic information

• Product Name: ETHYL 6-METHYL-2-PHENYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLATE
• Synonyms: BUTTPARK 14\05-92;ETHYL 6-METHYL-2-PHENYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLATE;3-(Ethoxycarbonyl)-6-methyl-2-phenylimidazo[1,2-a]pyridine
• CAS NO: 127801-87-0
• Molecular Formula: C₁₇H₁₆N₂O₂
• Molecular Weight: 280.32
• Mol File: 127801-87-0.mol

Chemical Properties

• Melting Point: 72-74 °C
• Appearance: /
• Density: 1.17±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 4.18±0.50(Predicted)
• CAS DataBase Reference: ETHYL 6-METHYL-2-PHENYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 6-METHYL-2-PHENYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLATE(127801-87-0)
• EPA Substance Registry System: ETHYL 6-METHYL-2-PHENYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLATE(127801-87-0)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 127801-87-0(Hazardous Substances Data)

Upstream product

• 1603-41-4 (5-methyl-pyridin-2-yl)amine 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 55919-47-6 ethyl 2-bromo-3-oxo-3-phenylpropionate 

Downstream Products

• 123533-42-6 6-Methyl-2-phenyl-imidazo[1,2-a]pyridine-3-carboxylic acid 

Relevant articles and documents

CBr4 Mediated Oxidative C-N Bond Formation: Applied in the Synthesis of Imidazo[1,2-α]pyridines and Imidazo[1,2-α]pyrimidines

The carbon tetrabromide mediated oxidative carbon-nitrogen bond formation of 2-aminopyridines or 2-aminopyrimidines with β-keto esters or 1,3-diones, leading to a variety of complex imidazo[1,2-α]pyridines or imidazo[1,2-α]pyrimidines, is reported. The re

Cu(I)-catalysed oxidative coupling of 2-aminopyridines with β-keto esters: Synthesis of imidazo[1,2-a]pyridine-3-carboxylates

A simple, economical, and environmentally friendly copper-catalysed direct oxidative C-N coupling of 2-aminopyridines with β-keto esters using air as oxidation agent for the creation of imidazo[1,2-a]pyridine-3-carboxylates is demonstrated. Imidazo[1,2-a]pyridine is the basic skeleton for a wide range of biological and pharmacological compounds.

Thermal and microwave-assisted rapid syntheses of substituted imidazo[1,2-a]pyridines under solvent- and catalyst-free conditions

Thermal and microwave-assisted rapid syntheses of highly substituted imidazo[1,2-a]pyridine derivatives by reaction of aminopyridines and -bromo - keto esters under solvent-free conditions are described. Reactions carried out under microwave irradiation give the highest yields of products in reaction times of less than two minutes. Georg Thieme Verlag Stuttgart New York.

Synthesis of imidazo[1,2-a]pyridines by the bis(acetyloxy)(phenyl)- λ3-iodane-Mediated oxidative coupling of 2-aminopyridines with β-keto esters and 1,3-diones

Imidazo[1,2-a]pyridine-3-carboxylates can be prepared directly from 2-aminopyridines and β-keto esters by using bis(acetyloxy)(phenyl)- λ3-iodane as an oxidant and boron trifluoride etherate as a catalyst. The amount of catalyst plays a key rol

TBAI-catalyzed oxidative coupling of aminopyridines with β-keto esters and 1,3-diones - Synthesis of imidazo[1,2-a]pyridines

TBAI could catalyze the direct oxidative C-N coupling of 2-aminopyridines with β-keto esters and 1,3-diones, which affords imidazo[1,2-a]pyridines as the products. The reaction was realized under metal-free conditions by using tert-butyl hydroperoxide (TB