CHNC(N)NCOCCONHCH₂CCH((C₇H₇NCH₃)CH₂CCC₆H₄NHCONHC₂H₅)(CH₂C₆H₃F₂)

Base Information

• Chemical Name: CHNC(N)NCOCCONHCH₂CCH((C₇H₇NCH₃)CH₂CCC₆H₄NHCONHC₂H₅)(CH₂C₆H₃F₂)
• CAS No.: 942612-42-2
• Molecular Formula: C₃₅H₃₃F₂N₇O₃
• Molecular Weight: 637.689
• Mol file: 942612-42-2.mol

Synonyms:CHNC(N)NCOCCONHCH₂CCH((C₇H₇NCH₃)CH₂CCC₆H₄NHCONHC₂H₅)(CH₂C₆H₃F₂)

Chemical Property of CHNC(N)NCOCCONHCH₂CCH((C₇H₇NCH₃)CH₂CCC₆H₄NHCONHC₂H₅)(CH₂C₆H₃F₂)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of CHNC(N)NCOCCONHCH₂CCH((C₇H₇NCH₃)CH₂CCC₆H₄NHCONHC₂H₅)(CH₂C₆H₃F₂)

There total 1 articles about CHNC(N)NCOCCONHCH₂CCH((C₇H₇NCH₃)CH₂CCC₆H₄NHCONHC₂H₅)(CH₂C₆H₃F₂) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

8-(2,6-difluorobenzyl)-5,8-dihydro-2-(4-ethylaminocarbonylaminophenyl)-3-(N-methyl-N-benzylaminomethyl)-5-oxoimidazo[1,2-a]pyrimidine-6-carboxylic acid + Propargylamine (2450-71-7) → CHNC(N)NCOCCONHCH2CCH((C7H7NCH3)CH2CCC6H4NHCONHC2H5)(CH2C6H3F2) (942612-42-2)

Guidance literature:

With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 18h;

DOI:10.1016/j.bmc.2007.04.065

Reference yield: 47.0%

CHNC(N)NCOCCONHCH2CCH((C7H7NCH3)CH2CCC6H4NHCONHC2H5)(CH2C6H3F2) (942612-42-2) + 1,8-diazido-3,6-dioxaoctane (59559-06-7,82055-94-5) → C41H45N13O5F2

Guidance literature:

With copper(II) sulfate; sodium L-ascorbate; In water; acetonitrile; tert-butyl alcohol; at 60 ℃;

DOI:10.1016/j.bmc.2007.04.065

Reference yield: 36.0%

CHNC(N)NCOCCONHCH2CCH((C7H7NCH3)CH2CCC6H4NHCONHC2H5)(CH2C6H3F2) (942612-42-2) + 1,5-diazido-3-oxapentane (24345-74-2) → C74H74N20O7F4

Guidance literature:

With copper(II) sulfate; sodium L-ascorbate; In water; acetonitrile; tert-butyl alcohol; at 60 ℃;

DOI:10.1016/j.bmc.2007.04.065

upstream raw materials:

Propargylamine