BIS(3,5-BIS(TRIMETHYLSILYL)PHENYL)PHOSPHINE OXIDE

Base Information

• Chemical Name: BIS(3,5-BIS(TRIMETHYLSILYL)PHENYL)PHOSPHINE OXIDE
• CAS No.: 187344-98-5
• Molecular Formula: C24H43 O P Si4
• Molecular Weight: 490.91
• Mol file: 187344-98-5.mol

Synonyms:Bis(3,5-bis(trimethylsilyl)phenyl)phosphineoxide

Chemical Property of BIS(3,5-BIS(TRIMETHYLSILYL)PHENYL)PHOSPHINE OXIDE

Chemical Property:

• PSA: 40.54000
• LogP: 4.37790

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

BIS-(3,5-BIS-(TRIMETHYLSILYL)PHENYL)PHOSPHINE OXIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of BIS(3,5-BIS(TRIMETHYLSILYL)PHENYL)PHOSPHINE OXIDE

There total 2 articles about BIS(3,5-BIS(TRIMETHYLSILYL)PHENYL)PHOSPHINE OXIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

phosphonic acid diethyl ester (762-04-9) + [3,5-bis(trimethylsilyl)phenyl]magnesium bromide → bis(3,5-bis(trimethylsilyl)phenyl)phosphine oxide (187344-98-5)

Guidance literature:

phosphonic acid diethyl ester; With sodium hydride; In tetrahydrofuran; mineral oil; at 0 - 20 ℃; for 2.5h; Inert atmosphere; Schlenk technique;

[3,5-bis(trimethylsilyl)phenyl]magnesium bromide; In tetrahydrofuran; mineral oil; at -12 - 20 ℃; for 26h; Inert atmosphere; Schlenk technique;

DOI:10.1021/jacs.1c05769

Reference yield:

[3,5-bis(trimethylsilyl)phenyl]magnesium bromide → bis(3,5-bis(trimethylsilyl)phenyl)phosphine oxide (187344-98-5)

Guidance literature:

With dibutyl hydrogen phosphite; potassium hydride; In diethyl ether; for 4h;

DOI:10.1021/ja00101a007

Reference yield: 90.0%

dimethylsulfide borane complex (13292-87-0) + bis(3,5-bis(trimethylsilyl)phenyl)phosphine oxide (187344-98-5) → C24H46BPSi4

Guidance literature:

bis(3,5-bis(trimethylsilyl)phenyl)phosphine oxide; With titanium(IV) isopropylate; 1,1,3,3-Tetramethyldisiloxane; In toluene; at 70 ℃; for 22.5h; Inert atmosphere;

dimethylsulfide borane complex; In toluene; at 0 - 20 ℃; for 24h; Inert atmosphere;

DOI:10.1021/jacs.1c05769

upstream raw materials:

phosphonic acid diethyl ester

Downstream raw materials:

bis[3,5-bis(trimethylsilyl)phenyl]chlorophosphine