(R)-S-Phenyl-S-((E)-1-trimethylsilyl-3-methylbut-1-enyl)-N-(toluene-p-sulfonyl)sulfoximine

Base Information

• Chemical Name: (R)-S-Phenyl-S-((E)-1-trimethylsilyl-3-methylbut-1-enyl)-N-(toluene-p-sulfonyl)sulfoximine
• CAS No.: 181489-43-0
• Molecular Formula: C₂₁H₂₉NO₃S₂Si
• Molecular Weight: 435.684
• Mol file: 181489-43-0.mol

Synonyms:(R)-S-Phenyl-S-((E)-1-trimethylsilyl-3-methylbut-1-enyl)-N-(toluene-p-sulfonyl)sulfoximine

Chemical Property of (R)-S-Phenyl-S-((E)-1-trimethylsilyl-3-methylbut-1-enyl)-N-(toluene-p-sulfonyl)sulfoximine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-S-Phenyl-S-((E)-1-trimethylsilyl-3-methylbut-1-enyl)-N-(toluene-p-sulfonyl)sulfoximine

There total 1 articles about (R)-S-Phenyl-S-((E)-1-trimethylsilyl-3-methylbut-1-enyl)-N-(toluene-p-sulfonyl)sulfoximine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

chloro-trimethyl-silane (75-77-4) + (S)-(+)-S-<(E)-3-Methyl-1-enyl>-S-phenyl-N-(toluene-p-sulfonyl)sulfoximine (102817-14-1) → (R)-S-Phenyl-S-((E)-1-trimethylsilyl-3-methylbut-1-enyl)-N-(toluene-p-sulfonyl)sulfoximine (181489-43-0)

Guidance literature:

With methyllithium; In tetrahydrofuran; diethyl ether; 1.) -78 deg C, 30 min, 2.) -78 deg C, 20 min.;

DOI:10.1039/p19960001673

Reference yield:

(R)-S-Phenyl-S-((E)-1-trimethylsilyl-3-methylbut-1-enyl)-N-(toluene-p-sulfonyl)sulfoximine (181489-43-0) → (2R)-2,3-Dimethylbutanoic acid (14287-61-7,15071-34-8,22160-11-8,27855-05-6)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrahydrofuran / 1.) -78 deg C, 30 min, 2.) r.t., 30 min

2: 30percent H₂O₂ / 1 h

With dihydrogen peroxide; In tetrahydrofuran;

DOI:10.1039/p19960001673

Reference yield:

(R)-S-Phenyl-S-((E)-1-trimethylsilyl-3-methylbut-1-enyl)-N-(toluene-p-sulfonyl)sulfoximine (181489-43-0) → (2S)-2,3-Dimethylbutanoic acid (15071-34-8)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrahydrofuran / 1.) -78 deg C, 30 min, 2.) r.t., 30 min

2: 30percent H₂O₂ / 1 h

With dihydrogen peroxide; In tetrahydrofuran;

DOI:10.1039/p19960001673

upstream raw materials:

chloro-trimethyl-silane

(S)-(+)-S-<(E)-3-Methyl-1-enyl>-S-phenyl-N-(toluene-p-sulfonyl)sulfoximine

Downstream raw materials:

(2R)-2,3-Dimethylbutanoic acid

(2S)-2,3-Dimethylbutanoic acid