tris[N-succinoyl[(valinyl)-5-fluorouridine] (benzyloxy)aminobutyl] isocyanurate

Base Information

• Chemical Name: tris[N-succinoyl[(valinyl)-5-fluorouridine] (benzyloxy)aminobutyl] isocyanurate
• CAS No.: 261783-80-6
• Molecular Formula: C₉₀H₁₁₄F₃N₁₅O₃₃
• Molecular Weight: 1990.97

Synonyms:tris[N-succinoyl[(valinyl)-5-fluorouridine] (benzyloxy)aminobutyl] isocyanurate

Chemical Property of tris[N-succinoyl[(valinyl)-5-fluorouridine] (benzyloxy)aminobutyl] isocyanurate

Chemical Property:

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Technology Process of tris[N-succinoyl[(valinyl)-5-fluorouridine] (benzyloxy)aminobutyl] isocyanurate

There total 2 articles about tris[N-succinoyl[(valinyl)-5-fluorouridine] (benzyloxy)aminobutyl] isocyanurate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

Tris<butyl> isocyanurate (153756-36-6) + (S)-2-Amino-3-methyl-butyric acid (2R,3S,4R,5R)-5-(5-fluoro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3,4-dihydroxy-tetrahydro-furan-2-ylmethyl ester; compound with toluene-4-sulfonic acid → [mono[N-succinoyl][(valinyl)-5-fluorouridine]-bis[N-succinoyl] (benzyloxy)amino butyl] isocyanurate (261783-78-2) + [bis[N-succinoyl][(valinyl)-5-fluorouridine]mono[N-succinoyl] (benzyloxy)amino butyl] isocyanurate + tris[N-succinoyl[(valinyl)-5-fluorouridine] (benzyloxy)aminobutyl] isocyanurate (261783-80-6)

Guidance literature:

With dmap; 1-hydroxy-7-aza-benzotriazole; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1016/S0968-0896(99)00248-5

Reference yield: 45.0%

Tris<butyl> isocyanurate (153756-36-6) + (S)-2-Amino-3-methyl-butyric acid (2R,3S,4R,5R)-5-(5-fluoro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3,4-dihydroxy-tetrahydro-furan-2-ylmethyl ester; compound with toluene-4-sulfonic acid → [bis[N-succinoyl][(valinyl)-5-fluorouridine]mono[N-succinoyl] (benzyloxy)amino butyl] isocyanurate + tris[N-succinoyl[(valinyl)-5-fluorouridine] (benzyloxy)aminobutyl] isocyanurate (261783-80-6)

Guidance literature:

With dmap; 1-hydroxy-7-aza-benzotriazole; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1016/S0968-0896(99)00248-5

upstream raw materials:

Tris<butyl> isocyanurate

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