3-Amino-2-methoxy-6-picoline

Base Information

Chemical Name:3-Amino-2-methoxy-6-picoline
CAS No.:186413-79-6
Molecular Formula:C7H10N2O
Molecular Weight:138.17
Hs Code.:2933399090
DSSTox Substance ID:DTXSID60442326
Wikidata:Q72490684
Mol file:186413-79-6.mol

Synonyms:3-Amino-2-methoxy-6-picoline;186413-79-6;2-methoxy-6-methylpyridin-3-amine;3-Amino-2-methoxy-6-methylpyridine;2-methoxy-6-methyl-3-pyridinamine;MFCD03095079;2-methoxy-3-amino-6-picoline;2-methoxy-6-methyl-pyridin-3-amine;3-Pyridinamine, 2-methoxy-6-methyl-;SCHEMBL1909505;3-Amino- 2-methoxy-6-picoline;DTXSID60442326;5-Amino-6-Methoxy-2-Methylpyridine;AKOS006279146;AC-5418;AM62384;CS-W003021;DS-0677;SB53145;SY021479;TS-01789;3-amino-2-methoxy-6-picoline, AldrichCPR;A4124;FT-0645953;FT-0653165;EN300-1295522;A813035;J-511550

Suppliers and Price of 3-Amino-2-methoxy-6-picoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Amino-2-methoxy-6-picoline
500mg
$ 75.00

TRC
3-Amino-2-methoxy-6-picoline
100mg
$ 60.00

TRC
3-Amino-2-methoxy-6-picoline
50mg
$ 45.00

SynQuest Laboratories
2-Methoxy-6-methylpyridin-3-amine 98%
5 g
$ 199.00

SynQuest Laboratories
2-Methoxy-6-methylpyridin-3-amine 98%
1 g
$ 87.00

SynQuest Laboratories
2-Methoxy-6-methylpyridin-3-amine 98%
25 g
$ 631.00

SynChem
3-AMINO-2-METHOXY-6-PICOLINE 95%
1 g
$ 100.00

Matrix Scientific
3-Amino-2-methoxy-6-picoline 95+%
10g
$ 1000.00

Matrix Scientific
3-Amino-2-methoxy-6-picoline 95+%
5g
$ 700.00

Crysdot
3-Amino-2-methoxy-6-picoline 95+%
5g
$ 99.00

Total 45 raw suppliers

Chemical Property of 3-Amino-2-methoxy-6-picoline

Chemical Property:

Vapor Pressure:0.027mmHg at 25°C
Refractive Index:1.553
Boiling Point:246.688 °C at 760 mmHg
PKA:5.05±0.10(Predicted)
Flash Point:102.993 °C
PSA：48.14000
Density:1.103 g/cm³
LogP:1.56200
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:138.079312947
Heavy Atom Count:10
Complexity:108

Purity/Quality:

97% ^*data from raw suppliers

3-Amino-2-methoxy-6-picoline ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC(=C(C=C1)N)OC
Uses 3-Amino-2-methoxy-6-picoline is a useful reagent in the synthesis of aminopyridinecarboxylic acid and derivatives as precursors for streptonigrin analogs.

Technology Process of 3-Amino-2-methoxy-6-picoline

There total 7 articles about 3-Amino-2-methoxy-6-picoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 186413-76-3
5-bromo-2-methoxy-6-methyl-3-nitropyridine

: 186413-79-6
3-amino-2-methoxy-6-methylpyridine

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; under 760 Torr;
DOI:10.1002/jhet.5570330670

Reference yield: 45.0%

: 112163-03-8
5-nitro-6-methoxy-2-methylpyridine

: 186413-79-6
3-amino-2-methoxy-6-methylpyridine

Guidance literature:: With 10 wt% Pd(OH)2 on carbon; ammonium formate; In methanol; at 50 ℃; for 20h; Inert atmosphere;

Reference yield:

: 68957-50-6
2-amino-5-bromo-6-methyl-3-nitropyridine

: 186413-79-6
3-amino-2-methoxy-6-methylpyridine

Guidance literature:: Multi-step reaction with 4 steps

1: 80 percent / NaNO₂, conc. H₂SO₄ / 0.5 h / 0 °C

2: 75 percent / POCl₃, pyridine / chlorobenzene / 1 h / Heating

3: 90 percent / Et₃N / 144 h / Heating

4: 95 percent / H₂ / 10percent Pd/C / ethanol / 760 Torr

With pyridine; sulfuric acid; hydrogen; triethylamine; sodium nitrite; trichlorophosphate; palladium on activated charcoal; In ethanol; chlorobenzene;
DOI:10.1002/jhet.5570330670