112163-03-8 Usage
Description
2-Methoxy-3-nitro-6-picoline, also known as 6-methoxynicotinic acid, is a yellow crystalline chemical compound with the molecular formula C7H8N2O3. It has a molecular weight of 168.15 g/mol and a melting point of 72-74°C. This substance is commonly used as an intermediate in the production of various organic compounds, including pharmaceuticals and pesticides. Additionally, it has potential applications as a corrosion inhibitor in the petroleum refining industry. Due to its hazardous nature, it should be handled with care to avoid adverse health effects.
Uses
Used in Pharmaceutical Industry:
2-Methoxy-3-nitro-6-picoline is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique chemical structure allows it to be a key component in the development of new drugs, contributing to the advancement of medicine and healthcare.
Used in Pesticide Industry:
In the pesticide industry, 2-Methoxy-3-nitro-6-picoline serves as an essential intermediate for the production of various agrochemicals. Its incorporation into these products helps in the development of effective and targeted pest control solutions, ensuring agricultural productivity and food security.
Used in Petroleum Refining Industry:
2-Methoxy-3-nitro-6-picoline has potential applications as a corrosion inhibitor in the petroleum refining process. Its ability to prevent corrosion in pipelines and storage tanks can significantly reduce maintenance costs and extend the lifespan of equipment, contributing to the efficiency and sustainability of the petroleum industry.
As a Chemical Intermediate:
2-Methoxy-3-nitro-6-picoline is used as a chemical intermediate for the synthesis of other organic compounds. Its versatile structure allows it to be a building block in the creation of various specialty chemicals, contributing to the diversity and innovation in the chemical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 112163-03-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,2,1,6 and 3 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 112163-03:
(8*1)+(7*1)+(6*2)+(5*1)+(4*6)+(3*3)+(2*0)+(1*3)=68
68 % 10 = 8
So 112163-03-8 is a valid CAS Registry Number.
InChI:InChI=1/C7H8N2O3/c1-5-3-4-6(9(10)11)7(8-5)12-2/h3-4H,1-2H3
112163-03-8Relevant articles and documents
Phenacylation of 6-methyl-beta-nitropyridin-2-ones and further heterocyclization of products
Babaev, Eugene V.,Rybakov, Victor B.
, (2020)
Reaction between the derivatives of 6-methyl-beta-nitropyridin-2-one and phenacyl bromides was studied, and the yields observed were extremely low. The pyridones were converted via chloropyridines to methoxyderivatives, which were N-phenacylated. N-Phenacyl derivatives of 4,6-dimethyl-5-nitropyridin-2-one under the action of base gave 5-hydroxy-8-nitroindolizine and under acidic conditions gave 5-methyl-6-nitrooxazole[3,2-a]pyridinium salt, which underwent recycization with MeONa to 5-methoxy-8-nitroindolizine.
ALKOXY-SUBSTITUTED PYRIDINYL DERIVATIVES AS LPA1 RECEPTOR ANTAGONISTS AND THEIR USE IN THE TREATMENT OF FIBROSIS
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Page/Page column 55; 57, (2019/12/28)
The present invention relates to pyridinyl derivatives of Formula (I) Formula (I) wherein R1, R2, R3, R4, R5, R6, Ar1, L, W, Z, m and n are as described in the description, their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of Formula (I), and especially to their use as LPA1 receptor modulators.