p-Nitrophenyl-3-{4-[bis-(4-methoxyphenyl)-hydroxymethyl]phenyl}-propionate

Base Information

• Chemical Name: p-Nitrophenyl-3-{4-[bis-(4-methoxyphenyl)-hydroxymethyl]phenyl}-propionate
• CAS No.: 178313-89-8
• Molecular Formula: C₃₀H₂₇NO₇
• Molecular Weight: 513.547
• Mol file: 178313-89-8.mol

Synonyms:p-Nitrophenyl-3-{4-[bis-(4-methoxyphenyl)-hydroxymethyl]phenyl}-propionate

Chemical Property of p-Nitrophenyl-3-{4-[bis-(4-methoxyphenyl)-hydroxymethyl]phenyl}-propionate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of p-Nitrophenyl-3-{4-[bis-(4-methoxyphenyl)-hydroxymethyl]phenyl}-propionate

There total 6 articles about p-Nitrophenyl-3-{4-[bis-(4-methoxyphenyl)-hydroxymethyl]phenyl}-propionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

p-Nitrophenyl-3-{4-[bis-(4-methoxyphenyl)-methyl]-phenyl}-propionate (178313-88-7) → p-Nitrophenyl-3-{4-[bis-(4-methoxyphenyl)-hydroxymethyl]phenyl}-propionate (178313-89-8)

Guidance literature:

With lead dioxide; acetic acid;

DOI:10.1016/0040-4020(96)00337-7

Reference yield:

(E)-p-formylcinnamic acid (66885-68-5) → p-Nitrophenyl-3-{4-[bis-(4-methoxyphenyl)-hydroxymethyl]phenyl}-propionate (178313-89-8)

Guidance literature:

Multi-step reaction with 4 steps

1: H₂ / 5percent Pd/C

2: 41 percent / glacial AcOH, conc. H₂SO₄ / Ambient temperature

3: 99 percent / N,N'-dicyclohexylcarbodiimide, pyridine / dioxane / Ambient temperature

4: 50 percent / glacial AcOH, PbO₂

With pyridine; sulfuric acid; hydrogen; lead dioxide; acetic acid; dicyclohexyl-carbodiimide; palladium on activated charcoal; In 1,4-dioxane;

DOI:10.1016/0040-4020(96)00337-7

Reference yield:

4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) → p-Nitrophenyl-3-{4-[bis-(4-methoxyphenyl)-hydroxymethyl]phenyl}-propionate (178313-89-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 99 percent / N,N'-dicyclohexylcarbodiimide, pyridine / dioxane / Ambient temperature

2: 50 percent / glacial AcOH, PbO₂

With pyridine; lead dioxide; acetic acid; dicyclohexyl-carbodiimide; In 1,4-dioxane;

DOI:10.1016/0040-4020(96)00337-7

upstream raw materials:

p-Nitrophenyl-3-{4-[bis-(4-methoxyphenyl)-methyl]-phenyl}-propionate

4-nitro-phenol

4-formyldihydrocinnamic acid

methoxybenzene

Downstream raw materials:

p-Nitrophenyl-3-{4-[bis-(4-methoxyphenyl)-chlormethyl]-phenyl}-propionate