Toluene-4-sulfonic acid (E)-(2S,3S)-3-(tert-butyl-dimethyl-silanyloxy)-2,4-dimethyl-hex-4-enyl ester

Base Information

Chemical Name:Toluene-4-sulfonic acid (E)-(2S,3S)-3-(tert-butyl-dimethyl-silanyloxy)-2,4-dimethyl-hex-4-enyl ester
CAS No.:136061-44-4
Molecular Formula:C₂₁H₃₆O₄SSi
Molecular Weight:412.666
Hs Code.:

Synonyms:Toluene-4-sulfonic acid (E)-(2S,3S)-3-(tert-butyl-dimethyl-silanyloxy)-2,4-dimethyl-hex-4-enyl ester

Suppliers and Price of Toluene-4-sulfonic acid (E)-(2S,3S)-3-(tert-butyl-dimethyl-silanyloxy)-2,4-dimethyl-hex-4-enyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Toluene-4-sulfonic acid (E)-(2S,3S)-3-(tert-butyl-dimethyl-silanyloxy)-2,4-dimethyl-hex-4-enyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Toluene-4-sulfonic acid (E)-(2S,3S)-3-(tert-butyl-dimethyl-silanyloxy)-2,4-dimethyl-hex-4-enyl ester

There total 10 articles about Toluene-4-sulfonic acid (E)-(2S,3S)-3-(tert-butyl-dimethyl-silanyloxy)-2,4-dimethyl-hex-4-enyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 136061-43-3
Toluene-4-sulfonic acid (E)-(2S,3S)-3-hydroxy-2,4-dimethyl-hex-4-enyl ester

: 18162-48-6
tert-butyldimethylsilyl chloride

: 136061-44-4
Toluene-4-sulfonic acid (E)-(2S,3S)-3-(tert-butyl-dimethyl-silanyloxy)-2,4-dimethyl-hex-4-enyl ester

Guidance literature:: With 1H-imidazole; In N,N-dimethyl-formamide; at 22 ℃; for 15h;

Reference yield:

: 21665-16-7
O¹,O²;O⁵,O⁶-diisopropylidene-3-methylene-α-D-ribo-3-deoxy-hexofuranose

: 136061-44-4
Toluene-4-sulfonic acid (E)-(2S,3S)-3-(tert-butyl-dimethyl-silanyloxy)-2,4-dimethyl-hex-4-enyl ester

Guidance literature:: Multi-step reaction with 10 steps

1: 85 percent / H₂, Et₃N / 10percent Pd/C / methanol / 5 h / 22 °C

2: 84 percent / 0.1 N H₂SO₄ / methanol / 5 h / 22 °C

3: 93 percent / pyridine / 20 h / 22 °C

4: 88 percent / LiAlH₄ / diethyl ether / 3 h / 35 °C

5: 93 percent / pyridiniumchloromate, Al₂O₃, NaOAc / CH₂Cl₂ / 24 h / 22 °C

6: nBuLi, (PhS)2 / tetrahydrofuran; benzene / 2.5 h / 22 °C / Irradiation

7: 76 percent / 1.4 N H₂SO₄ / dioxane / 48 h / 22 °C

9: 93 percent / pyridine / 20 h / 22 °C

10: 92 percent / imidazole / dimethylformamide / 15 h / 22 °C

With pyridine; 1H-imidazole; aluminum oxide; lithium aluminium tetrahydride; n-butyllithium; pyridiniumchloromate; sulfuric acid; hydrogen; sodium acetate; triethylamine; diphenyldisulfane; palladium on activated charcoal; In tetrahydrofuran; 1,4-dioxane; methanol; diethyl ether; dichloromethane; N,N-dimethyl-formamide; benzene;

Reference yield:

: 26291-75-8,81114-49-0,109200-09-1,128461-80-3
(R)-1-((3aR,5S,6R,6aR)-2,2,6-trimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl)ethane-1,2-diol

: 136061-44-4
Toluene-4-sulfonic acid (E)-(2S,3S)-3-(tert-butyl-dimethyl-silanyloxy)-2,4-dimethyl-hex-4-enyl ester

Guidance literature:: Multi-step reaction with 8 steps

1: 93 percent / pyridine / 20 h / 22 °C

2: 88 percent / LiAlH₄ / diethyl ether / 3 h / 35 °C

3: 93 percent / pyridiniumchloromate, Al₂O₃, NaOAc / CH₂Cl₂ / 24 h / 22 °C

4: nBuLi, (PhS)2 / tetrahydrofuran; benzene / 2.5 h / 22 °C / Irradiation

5: 76 percent / 1.4 N H₂SO₄ / dioxane / 48 h / 22 °C

7: 93 percent / pyridine / 20 h / 22 °C

8: 92 percent / imidazole / dimethylformamide / 15 h / 22 °C

With pyridine; 1H-imidazole; aluminum oxide; lithium aluminium tetrahydride; n-butyllithium; pyridiniumchloromate; sulfuric acid; sodium acetate; diphenyldisulfane; In tetrahydrofuran; 1,4-dioxane; diethyl ether; dichloromethane; N,N-dimethyl-formamide; benzene;