(R)-(+)-N-(2,2-Dimethoxyethyl)-3-(3,4-dimethoxyphenyl)-2-hydroxypropionate

Base Information

Chemical Name:(R)-(+)-N-(2,2-Dimethoxyethyl)-3-(3,4-dimethoxyphenyl)-2-hydroxypropionate
CAS No.:170801-79-3
Molecular Formula:C₁₅H₂₃NO₆
Molecular Weight:313.351
Hs Code.:

Synonyms:(R)-(+)-N-(2,2-Dimethoxyethyl)-3-(3,4-dimethoxyphenyl)-2-hydroxypropionate

Suppliers and Price of (R)-(+)-N-(2,2-Dimethoxyethyl)-3-(3,4-dimethoxyphenyl)-2-hydroxypropionate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R)-(+)-N-(2,2-Dimethoxyethyl)-3-(3,4-dimethoxyphenyl)-2-hydroxypropionate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-(+)-N-(2,2-Dimethoxyethyl)-3-(3,4-dimethoxyphenyl)-2-hydroxypropionate

There total 3 articles about (R)-(+)-N-(2,2-Dimethoxyethyl)-3-(3,4-dimethoxyphenyl)-2-hydroxypropionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.3%

: 54814-41-4,54640-00-5,54910-31-5
3-(3,4-dimethoxy-phenyl)-2-hydroxy-propionic acid methyl ester

: 22483-09-6
2,2-dimethoxyethylamine

: 170801-79-3
(R)-(+)-N-(2,2-Dimethoxyethyl)-3-(3,4-dimethoxyphenyl)-2-hydroxypropionate

Guidance literature:: With toluene-4-sulfonic acid; at 140 ℃; for 1.5h;
DOI:10.1002/ardp.19953280604

Reference yield:

: 153381-08-9
Methyl (S)-(+)-3-(3,4 dimethoxyphenyl)-2-hydroxypropionate

: 170801-79-3
(R)-(+)-N-(2,2-Dimethoxyethyl)-3-(3,4-dimethoxyphenyl)-2-hydroxypropionate

Guidance literature:: Multi-step reaction with 3 steps

1: 98 percent / Ph₃P, DEAD / tetrahydrofuran; toluene / 18 h / Ambient temperature

2: 81 percent / NaOMe / methanol / 24 h / Ambient temperature

3: 95.3 percent / p-TsOH / 1.5 h / 140 °C

With sodium methylate; toluene-4-sulfonic acid; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; methanol; toluene;
DOI:10.1002/ardp.19953280604

Reference yield:

: 170801-78-2
Methyl (R)-(+)-2-benzoyloxy-3-(3,4-dimethoxyphenyl)propionate

: 170801-79-3
(R)-(+)-N-(2,2-Dimethoxyethyl)-3-(3,4-dimethoxyphenyl)-2-hydroxypropionate

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / NaOMe / methanol / 24 h / Ambient temperature

2: 95.3 percent / p-TsOH / 1.5 h / 140 °C

With sodium methylate; toluene-4-sulfonic acid; In methanol;
DOI:10.1002/ardp.19953280604