3'-deoxy-5'-O-(monomethoxytrityl)-N⁶-<2-(4-nitrophenyl)ethoxycarbonyl>adenylyl-<2'-P-<2-(4-nitrophenyl)ethyl>>->5'>-3'-deoxy-N⁶-<2-(4-nitrophenyl)ethoxycarbonyl>adenylyl-<2'-P-<2-(4-nitrophenyl)ethyl>>->5'>-3'-deoxy-N⁶,2'-O-bis<2-(4-nit...

Base Information

• Chemical Name: 3'-deoxy-5'-O-(monomethoxytrityl)-N⁶-<2-(4-nitrophenyl)ethoxycarbonyl>adenylyl-<2'-P-<2-(4-nitrophenyl)ethyl>>->5'>-3'-deoxy-N⁶-<2-(4-nitrophenyl)ethoxycarbonyl>adenylyl-<2'-P-<2-(4-nitrophenyl)ethyl>>->5'>-3'-deoxy-N⁶,2'-O-bis<2-(4-nit...
• CAS No.: 97777-00-9
• Molecular Formula: C₁₀₂H₉₅N₂₁O₃₄P₂
• Molecular Weight: 2220.94
• Mol file: 97777-00-9.mol

Synonyms:3'-deoxy-5'-O-(monomethoxytrityl)-N⁶-<2-(4-nitrophenyl)ethoxycarbonyl>adenylyl-<2'-P-<2-(4-nitrophenyl)ethyl>>->5'>-3'-deoxy-N⁶-<2-(4-nitrophenyl)ethoxycarbonyl>adenylyl-<2'-P-<2-(4-nitrophenyl)ethyl>>->5'>-3'-deoxy-N⁶,2'-O-bis<2-(4-nit...

Chemical Property of 3'-deoxy-5'-O-(monomethoxytrityl)-N⁶-<2-(4-nitrophenyl)ethoxycarbonyl>adenylyl-<2'-P-<2-(4-nitrophenyl)ethyl>>->5'>-3'-deoxy-N⁶-<2-(4-nitrophenyl)ethoxycarbonyl>adenylyl-<2'-P-<2-(4-nitrophenyl)ethyl>>->5'>-3'-deoxy-N⁶,2'-O-bis<2-(4-nit...

Chemical Property:

Purity/Quality:

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Useful:

Technology Process of 3'-deoxy-5'-O-(monomethoxytrityl)-N⁶-<2-(4-nitrophenyl)ethoxycarbonyl>adenylyl-<2'-P-<2-(4-nitrophenyl)ethyl>>->5'>-3'-deoxy-N⁶-<2-(4-nitrophenyl)ethoxycarbonyl>adenylyl-<2'-P-<2-(4-nitrophenyl)ethyl>>->5'>-3'-deoxy-N⁶,2'-O-bis<2-(4-nit...

There total 1 articles about 3'-deoxy-5'-O-(monomethoxytrityl)-N⁶-<2-(4-nitrophenyl)ethoxycarbonyl>adenylyl-<2'-P-<2-(4-nitrophenyl)ethyl>>->5'>-3'-deoxy-N⁶-<2-(4-nitrophenyl)ethoxycarbonyl>adenylyl-<2'-P-<2-(4-nitrophenyl)ethyl>>->5'>-3'-deoxy-N⁶,2'-O-bis<2-(4-nit... which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3'-deoxy-5'-O-(monomethoxytrityl)-N6-<2-(4-nitrophenyl)ethoxycarbonyl>adenosine 2'-<2-(4-nitrophenyl)ethyl diisopropylphosphoramidite> (156046-19-4) + 3'-deoxy-N6-<2-(4-nitrophenyl)ethoxycarbonyl>adenylyl-<2'-P-<2-(4-nitrophenyl)ethyl>>-> 5'>-3'-deoxy-N6,2'-O-bis<2-(4-nitrophenyl)ethoxycarbonyl>adenosine (162434-95-9) → 3'-deoxy-5'-O-(monomethoxytrityl)-N6-<2-(4-nitrophenyl)ethoxycarbonyl>adenylyl-<2'-P-<2-(4-nitrophenyl)ethyl>>->5'>-3'-deoxy-N6-<2-(4-nitrophenyl)ethoxycarbonyl>adenylyl-<2'-P-<2-(4-nitrophenyl)ethyl>>->5'>-3'-deoxy-N6,2'-O-bis<2-(4-nit... (97777-00-9)

Guidance literature:

With 1H-tetrazole; iodine; Yield given. Multistep reaction; 1) CH₃CN; 2) H₂O;

DOI:10.1080/15257779508012544

Reference yield: 92.0%

3'-deoxy-5'-O-(monomethoxytrityl)-N6-<2-(4-nitrophenyl)ethoxycarbonyl>adenylyl-<2'-P-<2-(4-nitrophenyl)ethyl>>->5'>-3'-deoxy-N6-<2-(4-nitrophenyl)ethoxycarbonyl>adenylyl-<2'-P-<2-(4-nitrophenyl)ethyl>>->5'>-3'-deoxy-N6,2'-O-bis<2-(4-nit... (97777-00-9) → 3'-deoxy-N6-[2-(4-nitrophenyl)ethoxycarbonyl]adenylyl-(2'-{OP-[2-(4-nitrophenyl)ethyl]}->5')-3'-deoxy-N6-[2-(4-nitrophenyl)ethoxycarbonyl]adenylyl-(2'-{OP-[2-(4-nitrophenyl)ethyl]}->5')-3'-deoxy-N6,2'-O-bis[2-(4-nitrophenyl)ethoxycarbonyl]a... (168772-71-2)

Guidance literature:

With toluene-4-sulfonic acid; In methanol; dichloromethane;

DOI:10.1080/15257779508012544

Reference yield: 69.0%

3'-deoxy-5'-O-(monomethoxytrityl)-N6-<2-(4-nitrophenyl)ethoxycarbonyl>adenylyl-<2'-P-<2-(4-nitrophenyl)ethyl>>->5'>-3'-deoxy-N6-<2-(4-nitrophenyl)ethoxycarbonyl>adenylyl-<2'-P-<2-(4-nitrophenyl)ethyl>>->5'>-3'-deoxy-N6,2'-O-bis<2-(4-nit... (97777-00-9) → 3'-deoxy-5'-O-(monomethoxytrityl)-N6-<2-(4nitrophenyl)ethoxycarbonyl>adenylyl-<2'-P-<2-(4-nitrophenyl)ethyl>>->5'>-3'-deoxy-N6-<2-(4-nitrophenyl)ethoxycarbonyl>adenylyl-<2'-P-<2-(4-nitrophenyl)ethyl>>->5'>-3'-deoxy-N6-<2-(4-nitrophenyl)... (168772-69-8)

Guidance literature:

With potassium carbonate; In methanol;

DOI:10.1080/15257779508012544

upstream raw materials:

3'-deoxy-5'-O-(monomethoxytrityl)-N⁶-<2-(4-nitrophenyl)ethoxycarbonyl>adenosine 2'-<2-(4-nitrophenyl)ethyl diisopropylphosphoramidite>

3'-deoxy-N⁶-<2-(4-nitrophenyl)ethoxycarbonyl>adenylyl-<2'-P-<2-(4-nitrophenyl)ethyl>>-> 5'>-3'-deoxy-N⁶,2'-O-bis<2-(4-nitrophenyl)ethoxycarbonyl>adenosine

Downstream raw materials:

3'-deoxy-N⁶-[2-(4-nitrophenyl)ethoxycarbonyl]adenylyl-(2'-{O^P-[2-(4-nitrophenyl)ethyl]}->5')-3'-deoxy-N⁶-[2-(4-nitrophenyl)ethoxycarbonyl]adenylyl-(2'-{O^P-[2-(4-nitrophenyl)ethyl]}->5')-3'-deoxy-N⁶,2'-O-bis[2-(4-nitrophenyl)ethoxycarbonyl]a...

3'-deoxy-5'-O-(monomethoxytrityl)-N⁶-<2-(4nitrophenyl)ethoxycarbonyl>adenylyl-<2'-P-<2-(4-nitrophenyl)ethyl>>->5'>-3'-deoxy-N⁶-<2-(4-nitrophenyl)ethoxycarbonyl>adenylyl-<2'-P-<2-(4-nitrophenyl)ethyl>>->5'>-3'-deoxy-N⁶-<2-(4-nitrophenyl)...