162434-95-9Relevant academic research and scientific papers
Nucleotides Part IL: Synthesis and characterization of cordycepin-trimer-vitamin and -lipid conjugates potential inhibitors of HIV-1 replication
Wasner, Marita,Sahadolnik, Robert J.,Horvath, Susan E.,Adelson, Martin E.,Kon, Ning,Guan, Ming-Xu,Henderson, Earl E.,Pfleiderer, Wolfgang
, p. 619 - 633 (2007/10/03)
The syntheses of biodegradable 2′- and 5′-ester and 2′- and 5′-carbonate conjugates of the antivirally active 3'′-deoxyadenylyl-(2′-5′)-3′-deoxyadenylyl-(2′- 5′)-3′-deoxyadenosine (cordycepin-trimer core) with the vitamins, E, D2, and A and the
Synthesis of trimeric cordycepin-vitamin conjugates as improved antiviral agents
Wasner,Pfleiderer
, p. 1101 - 1104 (2007/10/02)
The chemical syntheses of various cordycepin trimers carrying vitamin E,D2 and A via a succinate linker at the 2'-O- and 5'-O-position are described. The conjugates were characterized by physical means and used for biological investigations.
Nucleotides. Part XLIV. Synthesis, characterization, and biological activity of monomeric and trimeric cordycepin-cholesterol conjugates and inhibition of HIV-1 replication
Wasner,Henderson,Suhadolnik,Pfleiderer
, p. 1757 - 1767 (2007/10/02)
The antivirally active 3'-deoxyadenylyl-(2'-5')-3'-deoxyadenylyl-(2'-5')-3'-deoxyadenosine (cordycepin trimer core) was modified at the 2'- or 5'-terminus, by attachment of cholesterol via a carbonate bond (→15) or a succinate linker (→16 and 27) to impro
