156046-19-4Relevant academic research and scientific papers
Cholesterol conjugates of 2'5'-oligoadenylate derivatives and antiviral uses thereof
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, (2008/06/13)
A cholesterol-cordycepin conjugate having the formula STR1 wherein: n is an integer from 1 to 8; R1 is selected from the group of consisting of T, T' and Y; T is STR2 T' is STR3 where x is an integer from 1 to 18; Y is STR4 where m is zero, 1,
Nucleotides. Part XLIV. Synthesis, characterization, and biological activity of monomeric and trimeric cordycepin-cholesterol conjugates and inhibition of HIV-1 replication
Wasner,Henderson,Suhadolnik,Pfleiderer
, p. 1757 - 1767 (2007/10/02)
The antivirally active 3'-deoxyadenylyl-(2'-5')-3'-deoxyadenylyl-(2'-5')-3'-deoxyadenosine (cordycepin trimer core) was modified at the 2'- or 5'-terminus, by attachment of cholesterol via a carbonate bond (→15) or a succinate linker (→16 and 27) to impro
Nucleotides. Part XL. Synthesis and characterization of modified 2'-5' adenylate trimers - Potential antiviral agents
Schirmeister,Pfleiderer
, p. 10 - 22 (2007/10/02)
2'-5' Adenylate trimers 41-44 carrying the (tert-butyl)dimethylsilyl (tbds) group at the 3'-OH position of various sugar moieties were synthesized via the phosphoramidite method. The use of the (tert-butyloxy)carbony (boc) and (2-(4-nitrophenyl)ethylsulfo
