diisopropyl 1-hydroxy-1-phenylethylphosphonate

Base Information

• Chemical Name: diisopropyl 1-hydroxy-1-phenylethylphosphonate
• CAS No.: 92431-61-3
• Molecular Formula: C₁₄H₂₃O₄P
• Molecular Weight: 286.308
• Mol file: 92431-61-3.mol

Synonyms:diisopropyl 1-hydroxy-1-phenylethylphosphonate

Chemical Property of diisopropyl 1-hydroxy-1-phenylethylphosphonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of diisopropyl 1-hydroxy-1-phenylethylphosphonate

There total 2 articles about diisopropyl 1-hydroxy-1-phenylethylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

diisopropyl hydrogenphosphonate (1809-20-7) + acetophenone (98-86-2) → diisopropyl 1-hydroxy-1-phenylethylphosphonate (92431-61-3)

Guidance literature:

With n-butyllithium; In neat (no solvent); at 10 ℃; for 0.0833333h; Catalytic behavior; Schlenk technique; Inert atmosphere;

DOI:10.1021/ol5030713

Reference yield:

diisopropyl phosphite (691-96-3) + acetophenone (98-86-2) → diisopropyl 1-hydroxy-1-phenylethylphosphonate (92431-61-3)

Guidance literature:

With sodium isopropylate; In isopropyl alcohol;

upstream raw materials:

diisopropyl phosphite

acetophenone

diisopropyl hydrogenphosphonate