N-(4-methoxy-2,3-dimethylphenyl)acetamide

Base Information

Chemical Name:N-(4-methoxy-2,3-dimethylphenyl)acetamide
CAS No.:74783-55-4
Molecular Formula:C₁₁H₁₅NO₂
Molecular Weight:193.246
Hs Code.:
DSSTox Substance ID:DTXSID601269570
Nikkaji Number:J1.594.837J

Synonyms:N-(4-methoxy-2,3-dimethylphenyl)acetamide;74783-55-4;SCHEMBL5409015;ZLEYKMCBMFNDPJ-UHFFFAOYSA-N;DTXSID601269570

Suppliers and Price of N-(4-methoxy-2,3-dimethylphenyl)acetamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(4-methoxy-2,3-dimethylphenyl)acetamide

Chemical Property:

XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:193.110278721
Heavy Atom Count:14
Complexity:206

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(C=CC(=C1C)OC)NC(=O)C

Technology Process of N-(4-methoxy-2,3-dimethylphenyl)acetamide

There total 5 articles about N-(4-methoxy-2,3-dimethylphenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 81029-03-0
4-Methoxy-2,3-dimethylnitrobenzene

: 108-24-7
acetic anhydride

: 74783-55-4
4-acetamino-1-methoxy-2,3-dimethylbenzene

Guidance literature:: 4-Methoxy-2,3-dimethylnitrobenzene; With hydrogen; palladium 10% on activated carbon; In methanol; at 20 ℃; for 1h;

acetic anhydride; In ethyl acetate; for 2h; Heating / reflux;

Reference yield: 74.0%

: 2011-57-6
N-(4-hydroxy-2,3-dimethyl-phenyl)acetamide

: 74-88-4
methyl iodide

: 74783-55-4
4-acetamino-1-methoxy-2,3-dimethylbenzene

Guidance literature:: With sodium ethanolate; In ethanol; for 1h; Heating;

Reference yield:

: 526-75-0
2,3-Dimethylphenol

: 74783-55-4
4-acetamino-1-methoxy-2,3-dimethylbenzene

Guidance literature:: Multi-step reaction with 4 steps

1: 63.5 percent / NaNO₂; HCl conc. / aq. ethanol / 0 °C

2: 78 percent / aq. NH₃; H₂S

3: 84 percent / H₂O / 0.17 h / Heating

4: 74 percent / EtONa / ethanol / 1 h / Heating

With hydrogenchloride; ammonium hydroxide; hydrogen sulfide; sodium ethanolate; sodium nitrite; In ethanol; water;
DOI:10.1081/SCC-100104069