21(R)-Hydroxy Montelukast

Base Information

Chemical Name:21(R)-Hydroxy Montelukast
CAS No.:184763-26-6
Molecular Formula:C₃₅H₃₆ClNO₄S
Molecular Weight:602.194
Hs Code.:
UNII:D554UP7RBJ
Nikkaji Number:J870.103B
Mol file:184763-26-6.mol

Synonyms:21(R)-Hydroxy Montelukast;184763-26-6;Montelukast metabolite 5A;D554UP7RBJ;UNII-D554UP7RBJ;2-[1-[[(1R,3R)-1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-hydroxy-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanylmethyl]cyclopropyl]acetic acid;1-((((1R,3R)-1-(3-((1E)-2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-hydroxy-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid;Cyclopropaneacetic acid, 1-((((1R,3R)-1-(3-((1E)-2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-hydroxy-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)-;[R-[R*,R*-(E)]]-1-[[[1-[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxy-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]-cyclopropaneacetic Acid;SCHEMBL8609724;NS00116589;J-011839

Suppliers and Price of 21(R)-Hydroxy Montelukast

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
21(R)-HydroxyMontelukast
0.5mg
$ 275.00

American Custom Chemicals Corporation
21(R)-HYDROXY MONTELUKAST 95.00%
0.5MG
$ 797.50

Total 4 raw suppliers

Chemical Property of 21(R)-Hydroxy Montelukast

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:76-81°C
Refractive Index:1.689
Boiling Point:787.834°C at 760 mmHg
Flash Point:430.267°C
PSA：115.95000
Density:1.312g/cm³
LogP:8.43890
Storage Temp.:Amber Vial, -20°C Freezer, Under Inert Atmosphere
Solubility.:Acetone (Slightly), Chloroform (Slightly), Methanol (Slightly)
XLogP3:6.6
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:12
Exact Mass:601.2053575
Heavy Atom Count:42
Complexity:925

Purity/Quality:

97% ^*data from raw suppliers

21(R)-HydroxyMontelukast ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C1=CC=CC=C1C(CC(C2=CC=CC(=C2)C=CC3=NC4=C(C=CC(=C4)Cl)C=C3)SCC5(CC5)CC(=O)O)O)O
Isomeric SMILES:CC(C)(C1=CC=CC=C1[C@@H](C[C@H](C2=CC=CC(=C2)/C=C/C3=NC4=C(C=CC(=C4)Cl)C=C3)SCC5(CC5)CC(=O)O)O)O
Uses A metabolite of Montelukast (M568000).

Technology Process of 21(R)-Hydroxy Montelukast

There total 2 articles about 21(R)-Hydroxy Montelukast which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%