Technology Process of 4-(2,2-dicyanovinyl)-2,6-bis(3-bromopropyl)anisole
There total 8 articles about 4-(2,2-dicyanovinyl)-2,6-bis(3-bromopropyl)anisole which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
ammonium acetate;
for 0.0166667h;
Microwave irradiation;
Neat (no solvent);
Heating;
DOI:10.1016/j.tet.2012.02.014
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: titanium tetrachloride / dichloromethane / 4 h / -10 - 20 °C
1.2: 0.5 h / Cooling with ice
2.1: ammonium acetate / 0.02 h / Microwave irradiation; Neat (no solvent); Heating
With
ammonium acetate; titanium tetrachloride;
In
dichloromethane;
2.1: Knoevenagel condensation;
DOI:10.1016/j.tet.2012.02.014
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: potassium carbonate; sodium iodide / acetone / 48 h / 45 °C / Inert atmosphere
2.1: borane-THF / tetrahydrofuran / 3.5 h / -10 - 20 °C / Inert atmosphere
2.2: 3 h / 20 - 40 °C / Inert atmosphere
3.1: carbon tetrabromide; triphenylphosphine / dichloromethane / 24 h / 0 - 20 °C
4.1: titanium tetrachloride / dichloromethane / 4 h / -10 - 20 °C
4.2: 0.5 h / Cooling with ice
5.1: ammonium acetate / 0.02 h / Microwave irradiation; Neat (no solvent); Heating
With
borane-THF; carbon tetrabromide; ammonium acetate; titanium tetrachloride; potassium carbonate; triphenylphosphine; sodium iodide;
In
tetrahydrofuran; dichloromethane; acetone;
1.1: Williamson synthesis / 5.1: Knoevenagel condensation;
DOI:10.1016/j.tet.2012.02.014
