methyl (S)-2-amino-3-(3-bromo-4-hydroxyphenyl)propanoate hydrochloride

Base Information

Chemical Name:methyl (S)-2-amino-3-(3-bromo-4-hydroxyphenyl)propanoate hydrochloride
CAS No.:98778-83-7
Molecular Formula:C₁₀H₁₂BrNO₃*ClH
Molecular Weight:310.575
Hs Code.:

Synonyms:methyl (S)-2-amino-3-(3-bromo-4-hydroxyphenyl)propanoate hydrochloride

Suppliers and Price of methyl (S)-2-amino-3-(3-bromo-4-hydroxyphenyl)propanoate hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of methyl (S)-2-amino-3-(3-bromo-4-hydroxyphenyl)propanoate hydrochloride

Chemical Property:

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Useful:

Technology Process of methyl (S)-2-amino-3-(3-bromo-4-hydroxyphenyl)propanoate hydrochloride

There total 1 articles about methyl (S)-2-amino-3-(3-bromo-4-hydroxyphenyl)propanoate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 67-56-1
methanol

: 38739-13-8,7298-91-1
(2S)-2-amino-3-(3-bromo-4-hydroxyphenyl)propanoic acid

: 98778-83-7
methyl (S)-2-amino-3-(3-bromo-4-hydroxyphenyl)propanoate hydrochloride

Guidance literature:: With thionyl chloride; for 3h; Heating;
DOI:10.1021/jo00224a051

Reference yield: 90.0%

: 3978-80-1
Boc-Tyr-OH

: 98778-83-7
methyl (S)-2-amino-3-(3-bromo-4-hydroxyphenyl)propanoate hydrochloride

: 98778-72-4
N-(tert-butoxycarbonyl)-L-tyrosyl-3-bromo-L-tyrosine methyl ester

Guidance literature:: With benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine; In N,N-dimethyl-formamide; acetonitrile; at 0 - 20 ℃; for 16h;
DOI:10.1021/acs.jmedchem.9b01199

Reference yield:

: 98778-83-7
methyl (S)-2-amino-3-(3-bromo-4-hydroxyphenyl)propanoate hydrochloride

: 98778-75-7
cyclo-3-bromo-L-tyrosyl-L-tyrosine

Guidance literature:: Multi-step reaction with 2 steps

1: 89 percent / triethylamine, dicyclohexylcarbodiimide / dimethylformamide / 2 h / 0 °C

2: 1.) 98percent formic acid / 1.) 25 deg C, 2.) 2-BuOH, reflux

With formic acid; triethylamine; dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide;
DOI:10.1021/jo00224a051