4-benzyloxy-2,6-dimethylbenzoic acid methyl ester

Base Information

• Chemical Name: 4-benzyloxy-2,6-dimethylbenzoic acid methyl ester
• CAS No.: 306297-02-9
• Molecular Formula: C₁₇H₁₈O₃
• Molecular Weight: 270.328
• Mol file: 306297-02-9.mol

Synonyms:4-benzyloxy-2,6-dimethylbenzoic acid methyl ester

Chemical Property of 4-benzyloxy-2,6-dimethylbenzoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-benzyloxy-2,6-dimethylbenzoic acid methyl ester

There total 2 articles about 4-benzyloxy-2,6-dimethylbenzoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

4-(benzyloxy)-2,6-dimethylbenzoic acid (95741-45-0) + dimethyl sulfate (77-78-1) → 4-benzyloxy-2,6-dimethylbenzoic acid methyl ester (306297-02-9)

Guidance literature:

With potassium carbonate; In acetone; Heating;

Reference yield: 94.0%

4-(benzyloxy)-2,6-dimethylbenzoic acid (95741-45-0) + methyl iodide (74-88-4) → 4-benzyloxy-2,6-dimethylbenzoic acid methyl ester (306297-02-9)

Guidance literature:

With caesium carbonate; In DMF (N,N-dimethyl-formamide); at 25 ℃; for 17h;

Reference yield: 98.0%

4-benzyloxy-2,6-dimethylbenzoic acid methyl ester (306297-02-9) → methyl 4-hydroxy-2,6-dimethylbenzoate (83194-70-1)

Guidance literature:

With hydrogen; 10% palladium on activated carbon; In methanol; at 25 ℃; for 17h; under 2585.81 Torr;

upstream raw materials:

4-(benzyloxy)-2,6-dimethylbenzoic acid

dimethyl sulfate

methyl iodide

Downstream raw materials:

2,6-dimethyl-4-benzyloxy-benzyl alcohol

(4-benzyloxy-2,6-dimethyl-phenyl)-acetonitrile

methyl 4-hydroxy-2,6-dimethylbenzoate