2(R)-(-)-4-chlorophenylpropanoic acid

Base Information

Chemical Name:2(R)-(-)-4-chlorophenylpropanoic acid
CAS No.:105879-62-7
Molecular Formula:C₉H₉ClO₂
Molecular Weight:184.622
Hs Code.:

Synonyms:2(R)-(-)-4-chlorophenylpropanoic acid

Suppliers and Price of 2(R)-(-)-4-chlorophenylpropanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of 2(R)-(-)-4-chlorophenylpropanoic acid

Chemical Property:

Boiling Point:297.4±15.0 °C(Predicted)
Density:1.263±0.06 g/cm3(Predicted)

Purity/Quality:: 95% ^*data from raw suppliers

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Technology Process of 2(R)-(-)-4-chlorophenylpropanoic acid

There total 19 articles about 2(R)-(-)-4-chlorophenylpropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 51747-43-4
2-(4-chlorophenyl)-acrylic acid

: 105879-62-7
2(R)-(-)-4-chlorophenylpropanoic acid

Guidance literature:: With C₅₄H₆₈IrNP⁽¹⁺⁾*C₃₂H₁₂BF₂₄^(1-); hydrogen; caesium carbonate; In methanol; at 45 ℃; for 0.5h; under 4500.45 Torr; Pressure; Temperature; Time; Glovebox; Sealed tube;

Reference yield:

: 938-95-4
2-(4-Chloro-phenyl)-propionic acid

: 62784-66-1
bis(1-naphthyl)methanol

: 1116086-45-3
di(1-naphthyl)methyl (R)-2-(4-chlorophenyl)propanoate

: di(1-naphthyl)methyl (S)-2-(4-chlorophenyl)propanoate

: 105879-63-8
(S)-4-chloro-α-methylphenylacetic acid

: 105879-62-7
2(R)-(-)-4-chlorophenylpropanoic acid

Guidance literature:: With (R)-(+)-2-phenyl-2,3-dihydrobenzo[d]imidazo[2,1-b]thiazole; p-Methoxybenzoic anhydride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 12h; optical yield given as %ee; Resolution of racemate;
DOI:10.1002/ejoc.200800942

Reference yield:

: 286964-62-3
2-(4-chlorophenyl)propanal

: 105879-63-8
(S)-4-chloro-α-methylphenylacetic acid

: 105879-62-7
2(R)-(-)-4-chlorophenylpropanoic acid

Guidance literature:: With 9-oxyl-9-azabicyclo<3.3.1>nonan-3-one; oxygen; nitric acid; sodium nitrite; In water; acetonitrile; at 23 ℃; for 8h; under 760.051 Torr; Overall yield = 89 %; Overall yield = 164 mg; enantioselective reaction; Sealed tube;
DOI:10.1021/acs.orglett.6b01598