methyl 2-cyano-3-phenylpent-4-enoate

Base Information

• Chemical Name: methyl 2-cyano-3-phenylpent-4-enoate
• CAS No.: 1087162-37-5
• Molecular Formula: C₁₃H₁₃NO₂
• Molecular Weight: 215.252
• Mol file: 1087162-37-5.mol

Synonyms:methyl 2-cyano-3-phenylpent-4-enoate

Chemical Property of methyl 2-cyano-3-phenylpent-4-enoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2-cyano-3-phenylpent-4-enoate

There total 1 articles about methyl 2-cyano-3-phenylpent-4-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

cinnamyl methyl carbonate (85217-69-2,87802-71-9) + methyl 2-cyanoacetate (105-34-0) → methyl 2-cyano-3-phenylpent-4-enoate (1087162-37-5)

Guidance literature:

cinnamyl methyl carbonate; With 1,4-diaza-bicyclo[2.2.2]octane; bis(1,5-cyclooctadiene)diiridium(I) dichloride; C₃₇H₃₂NO₃P; In tetrahydrofuran; for 0.333333h;

methyl 2-cyanoacetate; In tetrahydrofuran; at 50 ℃; for 16h; Inert atmosphere;

DOI:10.1039/b809143a

Reference yield: 88.0%

methyl 2-cyano-3-phenylpent-4-enoate (1087162-37-5) → 3-phenyl-pent-4-ene nitrile (132769-61-0)

Guidance literature:

With lithium chloride; In water; N,N-dimethyl-formamide; for 1h; enantioselective reaction; Inert atmosphere; Reflux;

DOI:10.1021/acs.joc.8b01632

upstream raw materials:

cinnamyl methyl carbonate

methyl 2-cyanoacetate

Downstream raw materials:

3-phenyl-pent-4-ene nitrile