Technology Process of (S)-(2-(allyloxy)pent-4-ene-1,1-diyl)dibenzene
There total 12 articles about (S)-(2-(allyloxy)pent-4-ene-1,1-diyl)dibenzene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(2S)-1,1-diphenylpent-4-en-2-ol;
With
sodium hydride;
In
N,N-dimethyl-formamide;
at 0 - 20 ℃;
for 1h;
allyl bromide;
In
N,N-dimethyl-formamide;
at 20 ℃;
DOI:10.1021/jm049021k
- Guidance literature:
-
(2S)-1,1-diphenylpent-4-en-2-ol;
With
sodium hydride;
In
N,N-dimethyl-formamide;
at 0 - 20 ℃;
for 1h;
allyl bromide;
In
N,N-dimethyl-formamide;
at 0 - 20 ℃;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: dihydrogen peroxide / water / 20 °C / Inert atmosphere
2.1: 80 - 180 °C / Neat (no solvent); Pyrolysis under reduced pressure
3.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 20 °C / Cooling with ice; Inert atmosphere
4.1: (R,R)-Jacobsen catalyst; water / 72 h / 20 °C / Cooling with ice; Inert atmosphere
5.1: copper(l) iodide / tetrahydrofuran / -78 - 20 °C / Inert atmosphere
5.2: 0 °C / Inert atmosphere
6.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1 h / 0 °C / Inert atmosphere
6.2: 0 - 20 °C / Inert atmosphere
With
copper(l) iodide; (R,R)-Jacobsen catalyst; water; dihydrogen peroxide; sodium hydride; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; mineral oil;
DOI:10.1016/j.tetasy.2011.05.012
