(Trimethylsilyl)ethyl 4-iodobenzoate

Base Information

Chemical Name:(Trimethylsilyl)ethyl 4-iodobenzoate
CAS No.:305818-77-3
Molecular Formula:C₁₂H₁₇IO₂Si
Molecular Weight:348.256
Hs Code.:
DSSTox Substance ID:DTXSID901217392

Synonyms:(trimethylsilyl)ethyl 4-iodobenzoate;305818-77-3;SCHEMBL7641258;UMHAXMBMNPGUDM-UHFFFAOYSA-N;DTXSID901217392;Benzoic acid, 4-iodo-, 2-(trimethylsilyl)ethyl ester

Suppliers and Price of (Trimethylsilyl)ethyl 4-iodobenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (Trimethylsilyl)ethyl 4-iodobenzoate

Chemical Property:

Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:348.00425
Heavy Atom Count:16
Complexity:230

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C[Si](C)(C)CCOC(=O)C1=CC=C(C=C1)I

Technology Process of (Trimethylsilyl)ethyl 4-iodobenzoate

There total 1 articles about (Trimethylsilyl)ethyl 4-iodobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 2916-68-9
2-(Trimethylsilyl)ethanol

: 619-58-9
4-iodobenzoic acid

: 305818-77-3
2-(trimethylsilyl)ethyl 4-iodobenzoate

Guidance literature:: With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 20 ℃; for 24h;
DOI:10.1081/SCC-200057287

Reference yield: 94.0%

: 305818-77-3
2-(trimethylsilyl)ethyl 4-iodobenzoate

: 1066-54-2
trimethylsilylacetylene

: 860402-21-7
4-trimethylsilanylethynyl-benzoic acid 2-trimethylsilanyl-ethyl ester

Guidance literature:: With copper(l) iodide; diisopropylamine; bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; at 20 ℃; for 24h;
DOI:10.1081/SCC-200057287

Reference yield: 92.0%

: 28240-69-9
1,2-bis(dichlorophosphino)ethane

: borane tetrahydrofuran

: 305818-77-3
2-(trimethylsilyl)ethyl 4-iodobenzoate

: 812699-15-3
(CH₂BH₃P(C₆H₄COOCH₂CH₂Si(CH₃)3)2)2

Guidance literature:: With isopropylmagnesium bromide; In tetrahydrofuran; addn. of soln. of i-PrMgBr/THF to soln. of IC6H4COOC2H4SiMe3/THF for 5 min at -25°C; stirring for 1 h; addn. of soln. of (CH2PCl2)2/THF at -25°C; stirring for 3 h; quenching with MeOH; addn. of BH3*THF;stirring overnight at room temp.; removal of THF under reduced pressure, addn. of EtOH; pptn., filtration,washing with EtOH, drying on vac. line for 24 h;
DOI:10.1016/j.ica.2004.04.017