phenyl-N-[2,2,2-trichloro-1-(4-methoxyphenyl)ethyl]methanesulfonamide

Base Information

• Chemical Name: phenyl-N-[2,2,2-trichloro-1-(4-methoxyphenyl)ethyl]methanesulfonamide
• CAS No.: 1376938-31-6
• Molecular Formula: C₁₆H₁₆Cl₃NO₃S
• Molecular Weight: 408.733
• Mol file: 1376938-31-6.mol

Synonyms:phenyl-N-[2,2,2-trichloro-1-(4-methoxyphenyl)ethyl]methanesulfonamide

Chemical Property of phenyl-N-[2,2,2-trichloro-1-(4-methoxyphenyl)ethyl]methanesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of phenyl-N-[2,2,2-trichloro-1-(4-methoxyphenyl)ethyl]methanesulfonamide

There total 6 articles about phenyl-N-[2,2,2-trichloro-1-(4-methoxyphenyl)ethyl]methanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

phenyl-N-(2,2,2-trichloroethylidene)methanesulfonamide (90348-89-3) + methoxybenzene (100-66-3) → phenyl-N-[2,2,2-trichloro-1-(4-methoxyphenyl)ethyl]methanesulfonamide (1376938-31-6)

Guidance literature:

With phosphorus pentoxide; sulfuric acid; In tetrachloromethane; for 3h;

DOI:10.1134/S107042801204001X

Reference yield:

phenyl-methanesulfonic acid amide (4563-33-1) → Methoxychlor (72-43-5,105367-23-5) + phenyl-N-[2,2,2-trichloro-1-(4-methoxyphenyl)ethyl]methanesulfonamide (1376938-31-6)

Guidance literature:

Multi-step reaction with 3 steps

1: chlorine; sodium hydroxide / water / 2 h / 20 °C

2: 90 - 92 °C / Inert atmosphere

3: phosphorus pentoxide; sulfuric acid

With phosphorus pentoxide; sulfuric acid; chlorine; sodium hydroxide; In water;

DOI:10.1134/S107042801204001X

Reference yield:

N,N-dichlorophenylmethanesulfonamide (63636-97-5) → Methoxychlor (72-43-5,105367-23-5) + phenyl-N-[2,2,2-trichloro-1-(4-methoxyphenyl)ethyl]methanesulfonamide (1376938-31-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 - 92 °C / Inert atmosphere

2: phosphorus pentoxide; sulfuric acid

With phosphorus pentoxide; sulfuric acid;

DOI:10.1134/S107042801204001X

upstream raw materials:

N,N-dichlorophenylmethanesulfonamide

phenyl-N-(2,2,2-trichloroethylidene)methanesulfonamide

methoxybenzene

toluene