Technology Process of 4-fluoro-3-nitrobenzyl iodide
There total 6 articles about 4-fluoro-3-nitrobenzyl iodide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium iodide;
In
acetone;
at 20 ℃;
for 0.333333h;
Inert atmosphere;
DOI:10.1021/acs.joc.8b02554
- Guidance literature:
-
With
1H-imidazole; iodine;
In
dichloromethane;
at 60 - 70 ℃;
for 0.333333h;
Microwave irradiation;
Sealed tube;
DOI:10.1002/jhet.1619
- Guidance literature:
-
Multi-step reaction with 3 steps
1: sodium tetrahydroborate / methanol / 0.33 h / 0 - 20 °C / Inert atmosphere
2: 1,2-bis-(diphenylphosphino)ethane; bromine / dichloromethane / 2 h / -20 °C / Inert atmosphere
3: sodium iodide / acetone / 0.33 h / 20 °C / Inert atmosphere
With
sodium tetrahydroborate; bromine; 1,2-bis-(diphenylphosphino)ethane; sodium iodide;
In
methanol; dichloromethane; acetone;
DOI:10.1021/acs.joc.8b02554
