Carbamic acid, [1-(hydroxymethyl)-2-butynyl]-, 1,1-dimethylethyl ester, (R)-

Base Information

Chemical Name:Carbamic acid, [1-(hydroxymethyl)-2-butynyl]-, 1,1-dimethylethyl ester, (R)-
CAS No.:182495-17-6
Molecular Formula:C₁₀H₁₇NO₃
Molecular Weight:199.25
Hs Code.:
Mol file:182495-17-6.mol

Synonyms:Carbamic acid, [1-(hydroxymethyl)-2-butynyl]-, 1,1-dimethylethyl ester, (R)-

Suppliers and Price of Carbamic acid, [1-(hydroxymethyl)-2-butynyl]-, 1,1-dimethylethyl ester, (R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of Carbamic acid, [1-(hydroxymethyl)-2-butynyl]-, 1,1-dimethylethyl ester, (R)-

Chemical Property:

PSA：58.56000
LogP:1.28620

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Carbamic acid, [1-(hydroxymethyl)-2-butynyl]-, 1,1-dimethylethyl ester, (R)-

There total 2 articles about Carbamic acid, [1-(hydroxymethyl)-2-butynyl]-, 1,1-dimethylethyl ester, (R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 173065-20-8
1,1-dimethylethyl (4R)-2,2-dimethyl-4--3-oxazolidine carboxylate

: 182495-17-6
((R)-1-Hydroxymethyl-but-2-ynyl)-carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: TFA / methanol / 2 h / Ambient temperature

2: aq. Na₂CO₃, NaHCO₃ / dioxane / 1.) 0 deg C, overnight, 2.) 25 deg C, 8 h

With sodium hydrogencarbonate; sodium carbonate; trifluoroacetic acid; In 1,4-dioxane; methanol;
DOI:10.1016/0040-4020(96)00630-8

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: (R)-2-Amino-pent-3-yn-1-ol

: 182495-17-6
((R)-1-Hydroxymethyl-but-2-ynyl)-carbamic acid tert-butyl ester

Guidance literature:: With sodium hydrogencarbonate; sodium carbonate; In 1,4-dioxane; Yield given; 1.) 0 deg C, overnight, 2.) 25 deg C, 8 h;
DOI:10.1016/0040-4020(96)00630-8