ethyl-2-[3,5-di-iso-propyl-2-(methoxymethoxy)benzene] cyclopentene-1-carboxylate

Base Information

Chemical Name:ethyl-2-[3,5-di-iso-propyl-2-(methoxymethoxy)benzene] cyclopentene-1-carboxylate
CAS No.:330935-05-2
Molecular Formula:C₂₂H₃₂O₄
Molecular Weight:360.494
Hs Code.:

Synonyms:ethyl-2-[3,5-di-iso-propyl-2-(methoxymethoxy)benzene] cyclopentene-1-carboxylate

Suppliers and Price of ethyl-2-[3,5-di-iso-propyl-2-(methoxymethoxy)benzene] cyclopentene-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of ethyl-2-[3,5-di-iso-propyl-2-(methoxymethoxy)benzene] cyclopentene-1-carboxylate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl-2-[3,5-di-iso-propyl-2-(methoxymethoxy)benzene] cyclopentene-1-carboxylate

There total 5 articles about ethyl-2-[3,5-di-iso-propyl-2-(methoxymethoxy)benzene] cyclopentene-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 122539-74-6
2-trifluoromethanesulfonyloxy-cyclopent-1-enecarboxylic acid ethyl ester

: 330935-04-1
3,5-di-iso-propyl-2-(methoxymethoxy)benzene boronic acid

: 330935-05-2
ethyl-2-[3,5-di-iso-propyl-2-(methoxymethoxy)benzene] cyclopentene-1-carboxylate

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In ethanol; toluene; at 90 ℃; for 15h;
DOI:10.1021/jm020401k

Reference yield:

: 2934-05-6
2,4-diisopropylphenol

: 330935-05-2
ethyl-2-[3,5-di-iso-propyl-2-(methoxymethoxy)benzene] cyclopentene-1-carboxylate

Guidance literature:: Multi-step reaction with 5 steps

1.1: 99 percent / N-iodosuccinimide; p-toluenesulfonic acid / CH₂Cl₂ / 20 °C

2.1: NaH / dimethylformamide / 0.5 h / 0 °C

2.2: 97 percent / dimethylformamide / 3 h / 0 - 20 °C

3.1: n-BuLi / diethyl ether; tetrahydrofuran; hexane / 0.33 h / -78 °C

3.2: diethyl ether; tetrahydrofuran; hexane / 2.5 h / -78 - 20 °C

4.1: 6.6 g / aq. HCl / diethyl ether; tetrahydrofuran; hexane / 0.5 °C

5.1: 89 percent / Pd(PPh₃)4; aq. Na₂CO₃ / toluene; ethanol / 15 h / 90 °C

With hydrogenchloride; N-iodo-succinimide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; n-butyllithium; sodium hydride; sodium carbonate; toluene-4-sulfonic acid; In tetrahydrofuran; diethyl ether; ethanol; hexane; dichloromethane; N,N-dimethyl-formamide; toluene; 5.1: Suzuki coupling;
DOI:10.1021/jm020401k

Reference yield:

: 330935-02-9
2,4-di-iso-propyl-6-iodophenol

: 330935-05-2
ethyl-2-[3,5-di-iso-propyl-2-(methoxymethoxy)benzene] cyclopentene-1-carboxylate

Guidance literature:: Multi-step reaction with 4 steps

1.1: NaH / dimethylformamide / 0.5 h / 0 °C

1.2: 97 percent / dimethylformamide / 3 h / 0 - 20 °C

2.1: n-BuLi / diethyl ether; tetrahydrofuran; hexane / 0.33 h / -78 °C

2.2: diethyl ether; tetrahydrofuran; hexane / 2.5 h / -78 - 20 °C

3.1: 6.6 g / aq. HCl / diethyl ether; tetrahydrofuran; hexane / 0.5 °C

4.1: 89 percent / Pd(PPh₃)4; aq. Na₂CO₃ / toluene; ethanol / 15 h / 90 °C

With hydrogenchloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; n-butyllithium; sodium hydride; sodium carbonate; In tetrahydrofuran; diethyl ether; ethanol; hexane; N,N-dimethyl-formamide; toluene; 4.1: Suzuki coupling;
DOI:10.1021/jm020401k