2934-05-6

Basic information

• Product Name: 2,4-DIISOPROPYLPHENOL
• Synonyms: Phenol,2,4-bis(1-methylethyl)-;2,4-DIISOPROPYLPHENOL;2,4-bis(1-Methylethyl)-;Phenol, 2,4-diisopropyl-Phenol;2,4-bis(1-methylethyl)-pheno;2,4-Bis(1-methylethyl)phenol;2,4-diisopropyl-pheno;Phenol, 2,4-diisopropyl-
• CAS NO: 2934-05-6
• Molecular Formula: C₁₂H₁₈O
• Molecular Weight: 178.27
• EINECS: 220-906-1
• Product Categories: Organic Building Blocks;Oxygen Compounds;Phenols;Building Blocks;C9 to C20+;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds
• Mol File: 2934-05-6.mol
• Article Data: 16

Chemical Properties

• Melting Point: 37.99°C (estimate)
• Boiling Point: 79-80 °C(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 0.948 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0199mmHg at 25°C
• Refractive Index: n20/D 1.5130(lit.)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 10.76±0.18(Predicted)
• Water Solubility: Sparingly soluble at water (0.25 g/L at 25°C).
• CAS DataBase Reference: 2,4-DIISOPROPYLPHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DIISOPROPYLPHENOL(2934-05-6)
• EPA Substance Registry System: 2,4-DIISOPROPYLPHENOL(2934-05-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• RTECS: SL0800000
• Hazardous Substances Data: 2934-05-6(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 2934-05-6 differently. You can refer to the following data:
1. 2,4-Diisopropylphenol is a related compound of Propofol (P829750), as an antioxidant.
2. 2,4-Diisopropylphenol (Propofol EP Impurity A) is a related compound of Propofol (P829750), as an antioxidant.
3. 2,4-Diisopropylphenol may be used in the preparation of N,N-bis(3,5-diisopropyl-2-hydroxybenyl)-N′,N′-dimethyl-1,2-diaminoethane.

General Description

2,4-Diisopropylphenol, commonly known as 2,4-propofol, is an isomeric form of propofol. EC50 Microtox (5min, 25°C) assay value of 2,4-diisopropylphenol is 2x10-4mM. It is formed as one of the reaction products from the reaction between boron fluoride with isopropyl phenyl ether.

InChI:InChI=1/C12H18O/c1-8(2)10-5-6-12(13)11(7-10)9(3)4/h5-9,13H,1-4H3

Upstream product

• 187737-37-7 propene 
• 108-95-2 phenol 
• 88-69-7 2-(1-methylethyl)phenol 
• 99-89-8 4-Isopropylphenol 
• 2934-07-8 2,4,6-triisopropylphenol 
• 35946-91-9 2,5-Diisopropylphenol 
• 67-63-0 isopropyl alcohol 
• 622-85-5 propoxybenzene 
• 7601-90-3 perchloric acid 
• 7637-07-2 boron trifluoride 
• 2741-16-4 isopropoxybenzene 
• 64-17-5 ethanol 
• 120-80-9 benzene-1,2-diol 
• 90-05-1 2-methoxy-phenol 

Downstream Products

• 88-69-7 2-(1-methylethyl)phenol 
• 2934-07-8 2,4,6-triisopropylphenol 
• 2078-54-8 2,6-diisopropylphenol 
• 35946-91-9 2,5-Diisopropylphenol 
• 127502-55-0 2-Bromo-4,6-diisopropylphenol 
• 107613-50-3 tris(2,4-diisopropylphenyl)phosphate 
• 330935-02-9 2,4-di-iso-propyl-6-iodophenol 
• 127502-56-1 1-Benzyloxy-2-bromo-4,6-diisopropylbenzene 
• 127502-57-2 1-Benzyloxy-6-(p-fluorophenyl)-2,4-diisopropylbenzene 
• 1224157-47-4 2,4-diisopropylphenyl all-cis-4,7,10,13,16,19-docosahexaenoate 
• 96107-55-0 2,4-diisopropylphenyl diphenyl phosphate 
• 64532-94-1 isopropyl diphenyl phosphate 
• 55864-04-5 diphenyl-p-isopropylphenyl phosphate 
• 1398066-03-9 2,4-diisopropylphenyl oleate 

Relevant articles and documents

Guaiacol demethoxylation catalyzed by Re2O7 in ethanol

Re2O7 is used to convert guaiacol in alcohols at 280–320 °C. In ethanol, guaiacol is deoxygenated and alkylated, and the major products are phenol and alkylphenols (including ethylphenol, diethylphenol, diisopropylphenol, di-tert-butylphenol and 2,6-di-tert-butyl-4-ethylphenol), accounting for 97 mol% of all products after 6 hour reaction at 320 °C. Both catechol and phenol are the intermediates of guaiacol demethoxylation. Among the substituents, ethyl is directly provided by ethanol while isopropyl and tert-butyl are formed by the addition of methyl to ethyl step by step. In addition, Re2O7 has negligible activity for the saturation of benzene ring so it does not cause considerable over-consumption of reductant. The actual catalyst for guaiacol demethoxylation is likely a ReIV?VI species.

Method for preparing hydrocarbyl phenol by catalytic conversion of phenolic compound in presence of molybdenum-based catalyst

The invention discloses a method for preparing hydrocarbyl phenol by catalytic conversion of a phenolic compound in the presence of a molybdenum-based catalyst. The method comprises mixing a phenoliccompound, a molybdenum-based catalyst and a reaction solvent, adding the mixture into a sealed reactor, feeding gas into the reactor, heating the mixture to 150-350 DEG C, carrying out stirring for areaction for 0.5-2h, then filtering to remove a solid catalyst and carrying out rotary evaporateion to obtain a liquid product. The phenolic compound has a wide source, a cost is low, product alkyl phenol selectivity is high, an added value is high, alcohol or an alcohol-water mixture is used as a reaction solvent, environmental friendliness is realized, pollution is avoided, any inorganic acids and alkalis are avoided in the reaction process, the common environmental pollution problems in the biomass processing technology are solved, the reaction conditions are mild, the process can be carried out at a low temperature, high-efficiency conversion of the reactants can be realized without consuming hydrogen gas and the method is suitable for large-scale industrial trial production.

Catalytic performance of Al-MCM-48 molecular sieves for isopropylation of phenol with isopropyl acetate

Al-MCM-48 molecular sieves (Si/Al molar ratios = 25, 50, 75, and 100) were synthesized hydrothermally using cetyltrimethylammonium bromide as the structure directing template. The orderly arrangement of mesopores was evident from the low angle X-ray diffr