{4-[(1-{2-[methyl(propyl)amino]-2-oxoethyl}-1H-indazol-3-yl)methyl]-5-oxo-1-phenyl-4,5-dihydro-6H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-6-yl}acetic acid.

Base Information

Chemical Name:{4-[(1-{2-[methyl(propyl)amino]-2-oxoethyl}-1H-indazol-3-yl)methyl]-5-oxo-1-phenyl-4,5-dihydro-6H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-6-yl}acetic acid.
CAS No.:1228935-36-1
Molecular Formula:C₃₂H₃₁N₇O₄
Molecular Weight:577.643
Hs Code.:

Synonyms:{4-[(1-{2-[methyl(propyl)amino]-2-oxoethyl}-1H-indazol-3-yl)methyl]-5-oxo-1-phenyl-4,5-dihydro-6H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-6-yl}acetic acid.

Suppliers and Price of {4-[(1-{2-[methyl(propyl)amino]-2-oxoethyl}-1H-indazol-3-yl)methyl]-5-oxo-1-phenyl-4,5-dihydro-6H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-6-yl}acetic acid.

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of {4-[(1-{2-[methyl(propyl)amino]-2-oxoethyl}-1H-indazol-3-yl)methyl]-5-oxo-1-phenyl-4,5-dihydro-6H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-6-yl}acetic acid.

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of {4-[(1-{2-[methyl(propyl)amino]-2-oxoethyl}-1H-indazol-3-yl)methyl]-5-oxo-1-phenyl-4,5-dihydro-6H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-6-yl}acetic acid.

There total 5 articles about {4-[(1-{2-[methyl(propyl)amino]-2-oxoethyl}-1H-indazol-3-yl)methyl]-5-oxo-1-phenyl-4,5-dihydro-6H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-6-yl}acetic acid. which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1228935-35-0
benzyl {4-[(1-{2-[methyl(propyl)amino]-2-oxoethyl}-1H-indazol-3-yl)methyl]-5-oxo-1-phenyl-4,5-dihydro-6H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-6-yl}acetate

: 1228935-36-1
{4-[(1-{2-[methyl(propyl)amino]-2-oxoethyl}-1H-indazol-3-yl)methyl]-5-oxo-1-phenyl-4,5-dihydro-6H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-6-yl}acetic acid.

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In methanol; for 2h; under 3087.28 Torr; Parr shaker; Inert atmosphere;

Reference yield:

: 1228935-34-9
[3-({6-[2-(benzyloxy)-2-oxoethyl]-5-oxo-1-phenyl-5,6-dihydro-4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-4-yl}methyl)-1H-indazol-1-yl]acetic acid

: 1228935-36-1
{4-[(1-{2-[methyl(propyl)amino]-2-oxoethyl}-1H-indazol-3-yl)methyl]-5-oxo-1-phenyl-4,5-dihydro-6H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-6-yl}acetic acid.

Guidance literature:: Multi-step reaction with 2 steps

1: 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; N-ethyl-N,N-diisopropylamine / ethyl acetate; N,N-dimethyl-formamide / 72 h / 40 °C

2: hydrogen / palladium 10% on activated carbon / methanol / 2 h / 3087.28 Torr / Parr shaker; Inert atmosphere

With hydrogen; 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; N-ethyl-N,N-diisopropylamine; palladium 10% on activated carbon; In methanol; ethyl acetate; N,N-dimethyl-formamide;

Reference yield:

: tert-butyl-[3-({6-[2-(benzyloxy)-2-oxoethyl]-5-oxo-1-phenyl-5,6-dihydro-4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-4-yl}methyl)-1H-indazol-1-yl]acetate

: 1228935-36-1
{4-[(1-{2-[methyl(propyl)amino]-2-oxoethyl}-1H-indazol-3-yl)methyl]-5-oxo-1-phenyl-4,5-dihydro-6H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-6-yl}acetic acid.

Guidance literature:: Multi-step reaction with 3 steps

1: trifluoroacetic acid / dichloromethane / 15 h / 20 °C

2: 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; N-ethyl-N,N-diisopropylamine / ethyl acetate; N,N-dimethyl-formamide / 72 h / 40 °C

3: hydrogen / palladium 10% on activated carbon / methanol / 2 h / 3087.28 Torr / Parr shaker; Inert atmosphere

With hydrogen; 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; palladium 10% on activated carbon; In methanol; dichloromethane; ethyl acetate; N,N-dimethyl-formamide;