(+/-)-3,4-dihydro-2,2-dimethyl-3-(phenylseleno)-2H-benzodioxepin

Base Information

• Chemical Name: (+/-)-3,4-dihydro-2,2-dimethyl-3-(phenylseleno)-2H-benzodioxepin
• CAS No.: 132277-36-2
• Molecular Formula: C₁₇H₁₈O₂Se
• Molecular Weight: 333.289
• Mol file: 132277-36-2.mol

Synonyms:(+/-)-3,4-dihydro-2,2-dimethyl-3-(phenylseleno)-2H-benzodioxepin

Chemical Property of (+/-)-3,4-dihydro-2,2-dimethyl-3-(phenylseleno)-2H-benzodioxepin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+/-)-3,4-dihydro-2,2-dimethyl-3-(phenylseleno)-2H-benzodioxepin

There total 4 articles about (+/-)-3,4-dihydro-2,2-dimethyl-3-(phenylseleno)-2H-benzodioxepin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.0%

Phenylselenyl chloride (5707-04-0) + 2-(3-Methyl-but-2-enyloxy)-phenol (132277-33-9) → (+/-)-3,4-dihydro-2,2-dimethyl-3-(phenylseleno)-2H-benzodioxepin (132277-36-2)

Guidance literature:

In ethyl acetate; at -75 - 20 ℃; for 17h;

DOI:10.1021/ja952666c

Reference yield: 32.0%

Phenylselenyl chloride (5707-04-0) → (+/-)-3,4-dihydro-2,2-dimethyl-3-(phenylseleno)-2H-benzodioxepin (132277-36-2)

Guidance literature:

In ethyl acetate; at -78 ℃;

DOI:10.1016/S0040-4039(00)97054-0

Reference yield:

benzene-1,2-diol (120-80-9,19481-10-8,37349-32-9) → (+/-)-3,4-dihydro-2,2-dimethyl-3-(phenylseleno)-2H-benzodioxepin (132277-36-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 71 percent / K₂CO₃ / dimethylformamide / 24 h / 0 - 20 °C

2: 32 percent / ethyl acetate / 17 h / -75 - 20 °C

With potassium carbonate; In ethyl acetate; N,N-dimethyl-formamide;

DOI:10.1021/ja952666c

upstream raw materials:

Phenylselenyl chloride

2-(3-Methyl-but-2-enyloxy)-phenol

benzene-1,2-diol

prenyl bromide