N-(4-amino-2-chloro-3-pyridyl)-N-<(2'-cyano-4-biphenyl)methyl>pentanamide

Base Information

• Chemical Name: N-(4-amino-2-chloro-3-pyridyl)-N-<(2'-cyano-4-biphenyl)methyl>pentanamide
• CAS No.: 153953-00-5
• Molecular Formula: C₂₄H₂₃ClN₄O
• Molecular Weight: 418.926

Synonyms:N-(4-amino-2-chloro-3-pyridyl)-N-<(2'-cyano-4-biphenyl)methyl>pentanamide

Chemical Property of N-(4-amino-2-chloro-3-pyridyl)-N-<(2'-cyano-4-biphenyl)methyl>pentanamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(4-amino-2-chloro-3-pyridyl)-N-<(2'-cyano-4-biphenyl)methyl>pentanamide

There total 4 articles about N-(4-amino-2-chloro-3-pyridyl)-N-<(2'-cyano-4-biphenyl)methyl>pentanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-chloropyridine-3,4-diamine (39217-08-8) → N-(4-amino-2-chloro-3-pyridyl)-N-<(2'-cyano-4-biphenyl)methyl>pentanamide (153953-00-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 69 percent / tetrahydrofuran / Ambient temperature

2: 1.8 g / potassium tert-butoxide / various solvent(s) / 5 h

With potassium tert-butylate; In tetrahydrofuran;

DOI:10.1021/jm00037a014

Reference yield:

pentanoic anhydride (2082-59-9) → N-(4-amino-2-chloro-3-pyridyl)-N-<(2'-cyano-4-biphenyl)methyl>pentanamide (153953-00-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 69 percent / tetrahydrofuran / Ambient temperature

2: 1.8 g / potassium tert-butoxide / various solvent(s) / 5 h

With potassium tert-butylate; In tetrahydrofuran;

DOI:10.1021/jm00037a014

Reference yield:

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile (114772-54-2) + N-(4-amino-2-chloro-3-pyridyl)pentanamide (153953-01-6) → 2-butyl-4-chloro-3-(2'-cyanobiphenyl-4-ylmethyl)-3H-imidazo[4,5-c]pyridine (145047-33-2) + N-(4-amino-2-chloro-3-pyridyl)-N-<(2'-cyano-4-biphenyl)methyl>pentanamide (153953-00-5)

Guidance literature:

With potassium tert-butylate; In various solvent(s); for 5h;

DOI:10.1021/jm00037a014

upstream raw materials:

4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile

N-(4-amino-2-chloro-3-pyridyl)pentanamide

2-chloropyridine-3,4-diamine

pentanoic anhydride

Downstream raw materials:

4'-<(2-butyl-4,5-dihydro-4-oxo-3H-imidazo<4,5-c>pyridin-3-yl)methyl>biphenyl-2-carbonitrile

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 153953-00-5 N-(4-amino-2-chloro-3-pyridyl)-N-<(2'-cyano-4-biphenyl)methyl>pentanamide

Send

Send

Metric Ton KG G Pound L ML

Send

Send