(S)-2-methoxy-1-((2R,5S,6R)-2-methoxy-5,6-dimethyl-4-oxotetrahydro-2H-pyran-2-yl)-2-oxoethyl benzoate

Base Information

Chemical Name:(S)-2-methoxy-1-((2R,5S,6R)-2-methoxy-5,6-dimethyl-4-oxotetrahydro-2H-pyran-2-yl)-2-oxoethyl benzoate
CAS No.:250378-69-9
Molecular Formula:C₁₈H₂₂O₇
Molecular Weight:350.368
Hs Code.:

Synonyms:(S)-2-methoxy-1-((2R,5S,6R)-2-methoxy-5,6-dimethyl-4-oxotetrahydro-2H-pyran-2-yl)-2-oxoethyl benzoate

Suppliers and Price of (S)-2-methoxy-1-((2R,5S,6R)-2-methoxy-5,6-dimethyl-4-oxotetrahydro-2H-pyran-2-yl)-2-oxoethyl benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-2-methoxy-1-((2R,5S,6R)-2-methoxy-5,6-dimethyl-4-oxotetrahydro-2H-pyran-2-yl)-2-oxoethyl benzoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-2-methoxy-1-((2R,5S,6R)-2-methoxy-5,6-dimethyl-4-oxotetrahydro-2H-pyran-2-yl)-2-oxoethyl benzoate

There total 4 articles about (S)-2-methoxy-1-((2R,5S,6R)-2-methoxy-5,6-dimethyl-4-oxotetrahydro-2H-pyran-2-yl)-2-oxoethyl benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 250378-78-0
(S)-2-methoxy-1-((7R,9R,10S)-7-methoxy-9,10-dimethyl-8-oxa-1,4-dithiaspiro[4.5]decan-7-yl)-2-oxoethyl benzoate

: 250378-69-9
(S)-2-methoxy-1-((2R,5S,6R)-2-methoxy-5,6-dimethyl-4-oxotetrahydro-2H-pyran-2-yl)-2-oxoethyl benzoate

Guidance literature:: With bis-[(trifluoroacetoxy)iodo]benzene; In water; acetonitrile; at -5 - 20 ℃; for 3h;
DOI:10.1021/ol990936g

Reference yield:

: 98-88-4
benzoyl chloride

: 250378-69-9
(S)-2-methoxy-1-((2R,5S,6R)-2-methoxy-5,6-dimethyl-4-oxotetrahydro-2H-pyran-2-yl)-2-oxoethyl benzoate

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / pyridine; DMAP / 13 h / 20 °C

2: 80 percent / (CF₃CO₂)2IPh / acetonitrile; H₂O / 3 h / -5 - 20 °C

With pyridine; dmap; bis-[(trifluoroacetoxy)iodo]benzene; In water; acetonitrile;
DOI:10.1021/ol990936g

Reference yield:

: 250378-76-8
tert-Butyl syn-(4S,5R)-5-hydroxy-4-methyl-3-oxohexanoate

: 250378-69-9
(S)-2-methoxy-1-((2R,5S,6R)-2-methoxy-5,6-dimethyl-4-oxotetrahydro-2H-pyran-2-yl)-2-oxoethyl benzoate

Guidance literature:: Multi-step reaction with 4 steps

1: boron trifluoride diethyl etherate / dichloromethane / -40 °C

2: zinc(II) chloride / tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide / -78 - -40 °C

3: dmap; pyridine

4: water; bis-[(trifluoroacetoxy)iodo]benzene / acetonitrile / -5 °C

With pyridine; dmap; boron trifluoride diethyl etherate; water; bis-[(trifluoroacetoxy)iodo]benzene; zinc(II) chloride; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; dichloromethane; acetonitrile; 2: |Claisen Condensation;